ABI3 and ARHGAP9

Data Source:
BioGRID (two hybrid)

		ABI3	ARHGAP9
Description		ABI family member 3	Rho GTPase activating protein 9
Image		No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Cytoplasm Membrane Lamellipodium	Extracellular Region Cytoplasm Cytosol Secretory Granule Lumen
	Molecular Function	Protein Binding SH3 Domain Binding Identical Protein Binding	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding
	Biological Process	Peptidyl-tyrosine Phosphorylation Regulation Of Cell Migration	Signal Transduction Regulation Of GTPase Activity Neutrophil Degranulation Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways			Rho GTPase cycle Neutrophil degranulation
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Asthma ( 31619474) Family history of Alzheimer's disease ( 30617256) Prostate cancer ( 23535732) Refractive error ( 32231278)	Monocyte percentage of white cells ( 32888494)
Interacting Genes		77 interacting genes: ABI2 ABI3BP ACTN3 AGTR1 ARHGAP9 ARMC7 BAIAP2L2 BFSP2 BLOC1S5 CENPQ CEP170P1 CEP44 CYFIP2 DESI1 DTNB DTNBP1 EIF3H EIF3M EMILIN1 ENAH EVL FAM124B FARSA FBF1 GNG13 GOLM1 GRB2 HOMER1 HOMER2 HOMER3 IFT20 IHO1 KANK2 KIAA0408 KIFC3 KLC3 KLC4 KRT13 KRT14 KRT15 KRT24 KRT28 KRT31 KRT35 KRT36 KRT38 MAGEA12 MED29 MIS18A MRFAP1 MRFAP1L1 NCK2 NDEL1 NHSL2 NUP58 OIP5 PAK1 PAK2 PSMA1 RUFY3 RUNX1T1 SH3BP1 SMARCD1 SNAP23 SOS1 STX1A STX2 SUFU TMEM147 TRAF4 TXN2 VARS2 VASP WAS WASF1 WASF2 WASHC1	16 interacting genes: ABI3 APP CYSRT1 FASLG FHL2 GOLGA6A GOLGA6L9 HOMEZ MRPL38 NME7 RAC1 RBPMS RUNX1T1 SMAD9 SNRPC TSC22D4
Entrez ID		51225	64333
HPRD ID		05900	06449
Ensembl ID		ENSG00000108798	ENSG00000123329
Uniprot IDs		Q9P2A4	B3KQ74 J3KPQ4 Q9BRR9
PDB IDs			2P0D 2P0F 2P0H
Enriched GO Terms of Interacting Partners?
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