ARHGAP9 and TSC22D4

Data Source:
BioGRID (two hybrid)

		ARHGAP9	TSC22D4
Description		Rho GTPase activating protein 9	TSC22 domain family member 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Secretory Granule Lumen	Nucleus
	Molecular Function	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding	Protein Binding
	Biological Process	Signal Transduction Regulation Of GTPase Activity Neutrophil Degranulation Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Regulation Of Transcription By RNA Polymerase II Response To Osmotic Stress Negative Regulation Of Transcription, DNA-templated
Pathways		Rho GTPase cycle Neutrophil degranulation
Drugs
Diseases
GWAS		Monocyte percentage of white cells ( 32888494)	Brain morphology (MOSTest) ( 32665545) Platelet count ( 27863252) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		16 interacting genes: ABI3 APP CYSRT1 FASLG FHL2 GOLGA6A GOLGA6L9 HOMEZ MRPL38 NME7 RAC1 RBPMS RUNX1T1 SMAD9 SNRPC TSC22D4	63 interacting genes: ABLIM1 AIFM1 APIP ARHGAP9 BLZF1 CBX8 CCDC146 CCDC33 CCDC42 CCNK CDC23 CDK5R1 CKS2 CLU CTNNAL1 ENKD1 FBXW7 FRMD6 FXR2 GOLGA2 GORASP2 KPNA2 KRT40 LBP LMO1 LMO2 LNX1 LRP2BP MAD2L1 MTHFS MYLIP MYO15B NIF3L1 NOC4L NRBP1 NRBP2 PCBP1 PCDH17 PIH1D1 PIN1 POLR1C PPL PRKAA1 PRKAA2 PRNP PSMA1 RACK1 SACS SAT1 SMAD3 SMARCB1 SYT17 TEX11 TLE5 TRIM55 TRIM63 TSC22D1 TSPOAP1 UBLCP1 VBP1 ZBTB24 ZMYND10 ZNF580
Entrez ID		64333	81628
HPRD ID		06449	18231
Ensembl ID		ENSG00000123329	ENSG00000166925
Uniprot IDs		B3KQ74 J3KPQ4 Q9BRR9	B4DKI8 Q9Y3Q8
PDB IDs		2P0D 2P0F 2P0H
Enriched GO Terms of Interacting Partners?
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