ABI3 and KRT14

Data Source:
BioGRID (two hybrid)

		ABI3	KRT14
Description		ABI family member 3	keratin 14
Image		No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Cytoplasm Membrane Lamellipodium	Nucleus Cytoplasm Cytosol Intermediate Filament Keratin Filament Basal Part Of Cell Extracellular Exosome Cell Periphery
	Molecular Function	Protein Binding SH3 Domain Binding Identical Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Keratin Filament Binding
	Biological Process	Peptidyl-tyrosine Phosphorylation Regulation Of Cell Migration	Aging Epidermis Development Response To Zinc Ion Response To Ionizing Radiation Keratinization Hemidesmosome Assembly Hair Cycle Intermediate Filament Bundle Assembly Cornification
Pathways			Type I hemidesmosome assembly Keratinization Formation of the cornified envelope
Drugs			Zinc Zinc acetate
Diseases			Naegeli-Franceschetti-Jadassohn syndrome Dermatopathia pigmentosa reticularis Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
GWAS		Alzheimer's disease (late onset) ( 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Asthma ( 31619474) Family history of Alzheimer's disease ( 30617256) Prostate cancer ( 23535732) Refractive error ( 32231278)
Interacting Genes		77 interacting genes: ABI2 ABI3BP ACTN3 AGTR1 ARHGAP9 ARMC7 BAIAP2L2 BFSP2 BLOC1S5 CENPQ CEP170P1 CEP44 CYFIP2 DESI1 DTNB DTNBP1 EIF3H EIF3M EMILIN1 ENAH EVL FAM124B FARSA FBF1 GNG13 GOLM1 GRB2 HOMER1 HOMER2 HOMER3 IFT20 IHO1 KANK2 KIAA0408 KIFC3 KLC3 KLC4 KRT13 KRT14 KRT15 KRT24 KRT28 KRT31 KRT35 KRT36 KRT38 MAGEA12 MED29 MIS18A MRFAP1 MRFAP1L1 NCK2 NDEL1 NHSL2 NUP58 OIP5 PAK1 PAK2 PSMA1 RUFY3 RUNX1T1 SH3BP1 SMARCD1 SNAP23 SOS1 STX1A STX2 SUFU TMEM147 TRAF4 TXN2 VARS2 VASP WAS WASF1 WASF2 WASHC1	32 interacting genes: ABI2 ABI3 AMOT APC BFSP2 CTTNBP2 DST ENKD1 GAS8 HGS HSPA5 KIFC3 KRT1 KRT3 KRT5 KRT6C KRT72 KRT78 KRT79 KRT80 KRT81 KRT86 OIP5 PKP1 PRPH PUS10 SDCBP SMARCE1 TCHP TRADD UBASH3A USHBP1
Entrez ID		51225	3861
HPRD ID		05900	01017
Ensembl ID		ENSG00000108798	ENSG00000186847
Uniprot IDs		Q9P2A4	P02533
PDB IDs			3TNU 6JFV
Enriched GO Terms of Interacting Partners?
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