CERCAM and GLRX3

Data Source:
BioGRID (two hybrid)

		CERCAM	GLRX3
Description		cerebral endothelial cell adhesion molecule	glutaredoxin 3
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Plasma Membrane	Nucleus Cytosol Cell Cortex Z Disc Dendrite
	Molecular Function	Protein Binding Identical Protein Binding Procollagen Galactosyltransferase Activity	RNA Binding Protein Kinase C Binding Protein Binding Protein Disulfide Oxidoreductase Activity Identical Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding
	Biological Process	Cell Adhesion Leukocyte Cell-cell Adhesion Protein Phosphopantetheinylation	Regulation Of The Force Of Heart Contraction Cellular Iron Ion Homeostasis Negative Regulation Of Cardiac Muscle Hypertrophy [2Fe-2S] Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer
Pathways			Iron uptake and transport
Drugs
Diseases
GWAS		Body mass index ( 26426971) Systemic lupus erythematosus ( 26606652)	Alcohol dependence ( 26365420) Copper levels ( 26025379) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) HIV-1 susceptibility ( 21160409) Mean corpuscular volume ( 32888494) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Triglyceride levels x short total sleep time interaction (1df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		34 interacting genes: ABHD5 ATG9A CDC23 CREB5 CYSRT1 FANCL FKBP7 FNDC11 GEMIN4 GLRX3 GOPC HOXA1 KLHL38 KRTAP15-1 KRTAP26-1 KRTAP3-3 KRTAP6-2 KRTAP8-1 KRTAP9-3 LASP1 MAGED1 MKRN3 OTX1 P4HA3 POGZ POU4F2 RHOXF2 SFT2D1 SOHLH1 TENT5B UBL5 VENTX VGLL3 ZDHHC15	99 interacting genes: ADAMTSL3 ADAMTSL4 ALKBH3 BCL6 BOLA1 BOLA2 BOLA2B BOLA3 CA9 CBLB CCHCR1 CERCAM CGGBP1 CIAPIN1 COL8A1 EFEMP2 ERBB2 FAM118A FRA10AC1 GATA1 GMCL1 GNG13 GRN HEXD HSD3B7 IHO1 IKZF1 IL10 IRX6 KLHDC9 KRT31 KRT38 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP13-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-3 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE2D LNX1 LNX2 LRIG1 MAP3K3 MAPK6 MAPKBP1 MDFI METAP1 MOXD1 NADK NOTCH2NLA NTF4 OLFM3 PCSK5 PFDN5 PLEKHG4B PLSCR1 PRKCQ PRKCZ PRKD2 RCOR3 RECK RGS20 SMARCC1 SOX7 STAU1 STRA6 TCF4 TCL1B TLE5 TMEM25 TRAF1 TRIM36 TRIM42 UGP2 ZBTB44 ZNF124 ZNF148 ZNF23 ZNF426 ZNF490 ZNF512B ZNF544 ZNF774
Entrez ID		51148	10539
HPRD ID		16705	10153
Ensembl ID		ENSG00000167123	ENSG00000108010
Uniprot IDs		Q5T4B2	A0A140VJK1 O76003
PDB IDs			2DIY 2WZ9 2YAN 3ZYW
Enriched GO Terms of Interacting Partners?
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