GLRX3 and CA9

Data Source:
BioGRID (two hybrid, two hybrid)

		GLRX3	CA9
Description		glutaredoxin 3	carbonic anhydrase 9
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GO Annotations	Cellular Component	Nucleus Cytosol Cell Cortex Z Disc Dendrite	Nucleolus Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Microvillus Membrane
	Molecular Function	RNA Binding Protein Kinase C Binding Protein Binding Protein Disulfide Oxidoreductase Activity Identical Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding Hydro-lyase Activity
	Biological Process	Regulation Of The Force Of Heart Contraction Cellular Iron Ion Homeostasis Negative Regulation Of Cardiac Muscle Hypertrophy [2Fe-2S] Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer	Morphogenesis Of An Epithelium One-carbon Metabolic Process Bicarbonate Transport Response To Testosterone Response To Drug Secretion Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Pathways		Iron uptake and transport	Regulation of gene expression by Hypoxia-inducible Factor Reversible hydration of carbon dioxide
Drugs			Benzthiazide Benzthiazide Cyclothiazide Hydroflumethiazide Zonisamide Girentuximab Ellagic acid Sodium carbonate
Diseases
GWAS		Alcohol dependence ( 26365420) Copper levels ( 26025379) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) HIV-1 susceptibility ( 21160409) Mean corpuscular volume ( 32888494) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Triglyceride levels x short total sleep time interaction (1df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		99 interacting genes: ADAMTSL3 ADAMTSL4 ALKBH3 BCL6 BOLA1 BOLA2 BOLA2B BOLA3 CA9 CBLB CCHCR1 CERCAM CGGBP1 CIAPIN1 COL8A1 EFEMP2 ERBB2 FAM118A FRA10AC1 GATA1 GMCL1 GNG13 GRN HEXD HSD3B7 IHO1 IKZF1 IL10 IRX6 KLHDC9 KRT31 KRT38 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP13-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-3 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE2D LNX1 LNX2 LRIG1 MAP3K3 MAPK6 MAPKBP1 MDFI METAP1 MOXD1 NADK NOTCH2NLA NTF4 OLFM3 PCSK5 PFDN5 PLEKHG4B PLSCR1 PRKCQ PRKCZ PRKD2 RCOR3 RECK RGS20 SMARCC1 SOX7 STAU1 STRA6 TCF4 TCL1B TLE5 TMEM25 TRAF1 TRIM36 TRIM42 UGP2 ZBTB44 ZNF124 ZNF148 ZNF23 ZNF426 ZNF490 ZNF512B ZNF544 ZNF774	6 interacting genes: CAND1 CDH1 CSRP1 CTNNA1 CTNNB1 GLRX3
Entrez ID		10539	768
HPRD ID		10153	04417
Ensembl ID		ENSG00000108010	ENSG00000107159
Uniprot IDs		A0A140VJK1 O76003	A0A0S2Z3D0 Q16790
PDB IDs		2DIY 2WZ9 2YAN 3ZYW	2HKF 3IAI 5DVX 5FL4 5FL5 5FL6 6FE0 6FE1 6FE2 6G98 6G9U 6QN2 6QN5 6QN6 6QUT 6RQN 6RQQ 6RQU 6RQW 6Y74
Enriched GO Terms of Interacting Partners?
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