GLRX3 and LRIG1

Data Source:
BioGRID (two hybrid)

		GLRX3	LRIG1
Description		glutaredoxin 3	leucine rich repeats and immunoglobulin like domains 1
Image
GO Annotations	Cellular Component	Nucleus Cytosol Cell Cortex Z Disc Dendrite	Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Matrix
	Molecular Function	RNA Binding Protein Kinase C Binding Protein Binding Protein Disulfide Oxidoreductase Activity Identical Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding	Protein Binding
	Biological Process	Regulation Of The Force Of Heart Contraction Cellular Iron Ion Homeostasis Negative Regulation Of Cardiac Muscle Hypertrophy [2Fe-2S] Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer	Sensory Perception Of Sound Hair Cycle Process Otolith Morphogenesis Innervation
Pathways		Iron uptake and transport	Signaling by EGFR Negative regulation of MET activity
Drugs
Diseases
GWAS		Alcohol dependence ( 26365420) Copper levels ( 26025379) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) HIV-1 susceptibility ( 21160409) Mean corpuscular volume ( 32888494) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Triglyceride levels x short total sleep time interaction (1df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs) ( 23648065) Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin) ( 23648065) Antibody status in Tripanosoma cruzi seropositivity ( 24324551) Atrial fibrillation ( 30061737 29892015) Birth weight ( 31043758) Blood urea nitrogen levels ( 29403010) Carotid intima media thickness ( 21909108) Chronic kidney disease ( 29124443) Colorectal cancer ( 26151821) Colorectal cancer or advanced adenoma ( 30510241) Creatinine levels ( 29124443) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 29124443) Hyperuricemia ( 29124443) Intraocular pressure ( 30054594) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Non-glioblastoma glioma ( 28346443) Orofacial clefts ( 33137956) Pulse pressure ( 27841878) QRS duration ( 27577874 21076409 27659466) Red cell distribution width ( 32888494) Refractive error ( 32231278) Renal function-related traits (BUN) ( 22797727) Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482) Retinal detachment or retinal break ( 31816047) Serum uric acid levels ( 29124443) Systolic blood pressure ( 27841878) Type 2 diabetes ( 25760438) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		99 interacting genes: ADAMTSL3 ADAMTSL4 ALKBH3 BCL6 BOLA1 BOLA2 BOLA2B BOLA3 CA9 CBLB CCHCR1 CERCAM CGGBP1 CIAPIN1 COL8A1 EFEMP2 ERBB2 FAM118A FRA10AC1 GATA1 GMCL1 GNG13 GRN HEXD HSD3B7 IHO1 IKZF1 IL10 IRX6 KLHDC9 KRT31 KRT38 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP13-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-3 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE2D LNX1 LNX2 LRIG1 MAP3K3 MAPK6 MAPKBP1 MDFI METAP1 MOXD1 NADK NOTCH2NLA NTF4 OLFM3 PCSK5 PFDN5 PLEKHG4B PLSCR1 PRKCQ PRKCZ PRKD2 RCOR3 RECK RGS20 SMARCC1 SOX7 STAU1 STRA6 TCF4 TCL1B TLE5 TMEM25 TRAF1 TRIM36 TRIM42 UGP2 ZBTB44 ZNF124 ZNF148 ZNF23 ZNF426 ZNF490 ZNF512B ZNF544 ZNF774	5 interacting genes: CBL GLRX3 MICOS10-NBL1 NBL1 ZBTB16
Entrez ID		10539	26018
HPRD ID		10153	10057
Ensembl ID		ENSG00000108010	ENSG00000144749
Uniprot IDs		A0A140VJK1 O76003	Q96JA1
PDB IDs		2DIY 2WZ9 2YAN 3ZYW	4U7L 4U7M
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?