INSIG2 and PRLR

  • Data Source:
  • BioGRID (two hybrid)

INSIG2

PRLR

Description insulin induced gene 2 prolactin receptor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein B levels ( 32203549)
  • Cholesterol, total ( 24097068)
  • Depression in response to interferon-based therapy in chronic hepatitis C ( 27723809)
  • Heel bone mineral density ( 30598549 28869591)
  • LDL cholesterol ( 24097068 30275531)
  • LDL cholesterol levels ( 32203549 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Lumbar spine bone mineral density ( 22504420)
  • Monobrow ( 27182965)
  • Mosquito bite size ( 28199695)
  • Total cholesterol levels ( 30275531)
  • Advanced age-related macular degeneration ( 26691988)
  • Chronotype ( 30696823)
  • Metabolite levels ( 23823483)
  • Paneth cell defects in Crohn's disease ( 28352666)
  • Psychotic experience ( 31553412)
  • Response to lurasidone in schizophrenia ( 29730043)
Interacting Genes 46 interacting genes: ABHD4 AQP2 AQP6 ATP6V0B BIK CD40 CD79A CPLX4 CREB3L1 CYBC1 EBP FAM209A GJA8 GOLM1 GPR152 GPR37L1 GPX8 HSD17B13 IFNGR2 KIR2DL3 LAPTM5 LHFPL5 LMNA MMGT1 MUC1 NEMP1 PRLR PSCA PSMA7 PSMB1 PSMC3 PSMC5 PVR RNF5 SCAP SCN3B SLC16A10 SREBF2 STIM1 TMEM14B TMEM237 TMEM45B TMEM52B TMX2 VCP VMA21 20 interacting genes: CISH CREBBP CSH1 FBXW11 GH1 INSIG2 JAK2 NEK3 PLPP6 PPIA PRL PTPN11 SOCS2 SOCS3 TEC VAV1 VAV2 YWHAG YWHAZ ZAP70
Entrez ID 51141 5618
HPRD ID 16361 01457
Ensembl ID ENSG00000125629 ENSG00000113494
Uniprot IDs A0A024RAI2 B4DQ23 Q9Y5U4 P16471
PDB IDs 4J82 1BP3 2LFG 2N7I 3D48 3MZG 3N06 3N0P 3NCB 3NCC 3NCE 3NCF 4I18
Enriched GO Terms of Interacting Partners?
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