THAP4 and CMTM7

Data Source:
BioGRID (two hybrid)

		THAP4	CMTM7
Description		THAP domain containing 4	CKLF like MARVEL transmembrane domain containing 7
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component	Extracellular Space Membrane Integral Component Of Membrane
	Molecular Function	DNA Binding Protein Binding Heme Binding Identical Protein Binding Metal Ion Binding Peroxynitrite Isomerase Activity Nitric Oxide Binding	Cytokine Activity Protein Binding
	Biological Process	Tyrosine Metabolic Process Nitrate Metabolic Process	B-1a B Cell Differentiation Chemotaxis Signal Transduction
Pathways
Drugs
Diseases
GWAS		Brain structure ( 20171287) Platelet count ( 32888494) Prostate cancer ( 23535732) Thyroid stimulating hormone levels ( 32769997)	Copper levels ( 26025379) Hallux valgus ( 32131869) IgM levels ( 28628107) Metabolite levels ( 23823483) Mortality in heart failure ( 20400778) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		42 interacting genes: AGTRAP AIG1 AMD1 ANKRD46 APP BSND CACNG1 CD81 CLCA4 CMTM5 CMTM7 COL4A5 CPNE2 CTSA CYP4F2 DGAT2L6 FKBP7 GIMAP1 GPR37L1 IGFBP5 LAT LPAR3 MAL2 MAPK6 MOB4 MS4A1 NDRG4 PLP2 RMDN2 RTP2 SCAMP1 SLC30A8 SYP TMEM107 TMEM60 TMEM86A TMEM86B TNFRSF10D TPD52 TRIM54 TTPA YIPF6	47 interacting genes: ADTRP AGER AQP6 ARL13B B3GAT1 BIK BSCL2 CD74 CD79A CLSTN3 CREB3L1 DAGLA DNAJC1 ELOVL4 FAM174A FAM209A FFAR2 FRMD3 GGT7 GORAB HAS3 HIBADH HSD17B13 LDLRAD1 LHFPL5 LMNA MS4A4A MUC1 PAGE1 PIANP PSMD6 RETREG3 SDC3 SHISA3 SLC14A2 SLC30A8 SSMEM1 STX1A TCTA TEX29 THAP4 TMEM106C TMEM174 TMEM31 TMPRSS2 TMX2 TNFRSF17
Entrez ID		51078	112616
HPRD ID		11630	06988
Ensembl ID		ENSG00000176946	ENSG00000153551
Uniprot IDs		Q8WY91	F8WDZ3 Q96FZ5
PDB IDs		3IA8
Enriched GO Terms of Interacting Partners?
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