GEMIN4 and FBXL12

Data Source:
BioGRID (two hybrid)

		GEMIN4	FBXL12
Description		gem nuclear organelle associated protein 4	F-box and leucine rich repeat protein 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Cytosol Cajal Body Membrane Nuclear Body Small Nuclear Ribonucleoprotein Complex SMN Complex SMN-Sm Protein Complex Extracellular Exosome Gemini Of Coiled Bodies	Nucleus Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Ribonucleoprotein Complex Binding	Protein Binding
	Biological Process	Spliceosomal SnRNP Assembly RRNA Processing Import Into Nucleus	G2/M Transition Of Mitotic Cell Cycle Protein Polyubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Entrainment Of Circadian Clock By Photoperiod Post-translational Protein Modification Regulation Of Cell Cycle
Pathways		snRNP Assembly	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	Pursuit maintenance gain ( 29064472)
Interacting Genes		55 interacting genes: AGO2 ALPP CALCOCO2 CCDC185 CCT3 CDC20B CERCAM CFP DDX20 DHX9 DMPK FBXL12 FLAD1 GEMIN5 GLYR1 HR KANK2 KARS1 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP2-3 KRTAP2-4 KRTAP9-2 LGALS1 LGALS3 LY86 MORC4 NPPB NUFIP1 PIAS3 PSMB1 PTCD1 PTEN RAD51D RN7SL1 RNU1-1 RNU2-1 S1PR4 SNRPB SNRPD1 SNRPD2 SPG21 SPRY1 SQSTM1 SRRT STXBP2 STXBP3 TAP1 TOP1 UFC1 USP15 USP2 ZNF326 ZNF35	19 interacting genes: A2M ALDH3A1 APOE CDC37 CDKN1C DOCK8 ECSIT FBF1 FXYD3 GEMIN4 LNX1 MAST1 PSEN1 PSEN2 PSME3 RNF32 SMAD1 TGFBR1 UBE2D3
Entrez ID		50628	54850
HPRD ID		07370	12363
Ensembl ID		ENSG00000179409	ENSG00000127452
Uniprot IDs		I3L2C7 P57678 Q8WUM5	Q9NXK8
PDB IDs
Enriched GO Terms of Interacting Partners?
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