FBXL12 and FBF1

Data Source:
BioGRID (two hybrid)

		FBXL12	FBF1
Description		F-box and leucine rich repeat protein 12	Fas binding factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol SCF Ubiquitin Ligase Complex	Spindle Pole Centrosome Centriole Cytosol Ciliary Basal Body Apical Junction Complex Keratin Filament Ciliary Transition Fiber
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Protein Polyubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Entrainment Of Circadian Clock By Photoperiod Post-translational Protein Modification Regulation Of Cell Cycle	Apical Junction Assembly Cilium Assembly Establishment Of Epithelial Cell Polarity Ciliary Basal Body-plasma Membrane Docking
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Pursuit maintenance gain ( 29064472)	Coronary artery disease ( 29212778) White matter hyperintensity burden ( 25663218)
Interacting Genes		19 interacting genes: A2M ALDH3A1 APOE CDC37 CDKN1C DOCK8 ECSIT FBF1 FXYD3 GEMIN4 LNX1 MAST1 PSEN1 PSEN2 PSME3 RNF32 SMAD1 TGFBR1 UBE2D3	49 interacting genes: ABI3 ACCS APP BLZF1 CALCOCO2 CCDC102B CCDC85B CEP55 CEP63 CINP CLK1 DEUP1 DGCR6 FAS FBXL12 GATA1 GCC1 GOLGA2 HIF1AN IFT20 IKZF3 KRT13 KRT31 KRT40 MEOX2 MID2 MIPOL1 PNMA1 RBPMS RHOXF2 SSX2IP SUMO1 TADA2A TASOR2 TCEA2 TEX11 TLE5 TMCC2 TRAF1 TRAF2 TRIM23 TRIM27 TRIM29 TRIM54 TSGA10 TTC32 TUBGCP4 USHBP1 VPS37B
Entrez ID		54850	85302
HPRD ID		12363	10948
Ensembl ID		ENSG00000127452	ENSG00000188878
Uniprot IDs		Q9NXK8	Q8TES7
PDB IDs
Enriched GO Terms of Interacting Partners?
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