DEF6 and PBXIP1

Data Source:
BioGRID (two hybrid)

		DEF6	PBXIP1
Description		DEF6 guanine nucleotide exchange factor	PBX homeobox interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Filopodium Perinuclear Region Of Cytoplasm	Nucleus Cytosol Microtubule Membrane
	Molecular Function	Protein Binding	Transcription Corepressor Activity Protein Binding
	Biological Process		Multicellular Organism Development Cell Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity
Pathways
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Height ( 18391951) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Neutrophil count ( 32888494) Systemic lupus erythematosus ( 28714469) White blood cell count ( 32888494)	Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Inflammatory bowel disease ( 27569725) Prostate cancer ( 23535732)
Interacting Genes		32 interacting genes: APP ARHGAP22 BEGAIN CCDC88B CDC42 CDC42EP1 EIF4ENIF1 GOLGA6A GOLGA6L9 HOMEZ INCA1 INTS2 KIAA1328 KRT31 L3MBTL3 LCK PBXIP1 PLSCR1 PSMA1 PTK2 RAC1 RAC2 RAPGEF4 RASAL3 REL RHOA SAP18 SLU7 TCF4 TEPSIN ZAP70 ZNF688	27 interacting genes: BRPF1 CAMLG CAPN2 CCDC85B CCNC DAXX DEF6 DPPA2 ESR1 GABARAPL1 GMCL1 GRB2 KRTAP10-6 LCA5L MDFI MDM2 MORF4L1 PCBD2 PPTC7 PRKAA2 SGTA TSNAX UBQLN1 UBQLN4 WASHC3 ZMYND8 ZZZ3
Entrez ID		50619	57326
HPRD ID		10869	17823
Ensembl ID		ENSG00000023892	ENSG00000163346
Uniprot IDs		Q9H4E7	B4E0K4 Q96AQ6
PDB IDs
Enriched GO Terms of Interacting Partners?
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