Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
ATP2B4 and CD22
Data Source:
HPRD
(in vitro, in vivo)
ATP2B4
CD22
Description
ATPase plasma membrane Ca2+ transporting 4
CD22 molecule
Image
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Caveola
Membrane
Basolateral Plasma Membrane
Z Disc
T-tubule
Protein-containing Complex
Sperm Flagellum
Neuron Projection
Intracellular Membrane-bounded Organelle
Membrane Raft
Sperm Principal Piece
Glutamatergic Synapse
Integral Component Of Presynaptic Active Zone Membrane
Cytoplasm
Early Endosome
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Integral Component Of Membrane
Neuronal Cell Body Membrane
Recycling Endosome
Extracellular Exosome
Molecular Function
Calcium Transmembrane Transporter Activity, Phosphorylative Mechanism
Protein Binding
Calmodulin Binding
ATP Binding
Calcium Ion Transmembrane Transporter Activity
Sodium Channel Regulator Activity
ATPase-coupled Cation Transmembrane Transporter Activity
Protein Kinase Binding
PDZ Domain Binding
Protein Phosphatase 2B Binding
Nitric-oxide Synthase Inhibitor Activity
Metal Ion Binding
Calcium-dependent Protein Binding
Nitric-oxide Synthase Binding
Scaffold Protein Binding
IgM Binding
Signaling Receptor Binding
Protein Binding
Protein Phosphatase Binding
Carbohydrate Binding
Sialic Acid Binding
CD4 Receptor Binding
Biological Process
Neural Retina Development
Regulation Of Transcription By RNA Polymerase II
Cellular Calcium Ion Homeostasis
Spermatogenesis
Negative Regulation Of Gene Expression
Negative Regulation Of Nitric Oxide Mediated Signal Transduction
Urinary Bladder Smooth Muscle Contraction
Negative Regulation Of Angiogenesis
Hippocampus Development
Flagellated Sperm Motility
Positive Regulation Of Peptidyl-serine Phosphorylation
Ion Transmembrane Transport
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Nitric Oxide Biosynthetic Process
Negative Regulation Of Nitric-oxide Synthase Activity
Regulation Of Cytosolic Calcium Ion Concentration
Response To Hydrostatic Pressure
Calcium Ion Transmembrane Transport
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Cellular Response To Epinephrine Stimulus
Calcium Ion Transmembrane Import Into Cytosol
Calcium Ion Import Across Plasma Membrane
Negative Regulation Of The Force Of Heart Contraction
Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process
Transport Across Blood-brain Barrier
Negative Regulation Of Arginine Catabolic Process
Calcium Ion Export
Negative Regulation Of Peptidyl-cysteine S-nitrosylation
Regulation Of Sodium Ion Transmembrane Transport
Negative Regulation Of Cellular Response To Vascular Endothelial Growth Factor Stimulus
Regulation Of Cell Cycle G1/S Phase Transition
Positive Regulation Of Protein Localization To Plasma Membrane
Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Negative Regulation Of Citrulline Biosynthetic Process
Regulation Of Cardiac Conduction
Cellular Response To Acetylcholine
Positive Regulation Of CAMP-dependent Protein Kinase Activity
Negative Regulation Of Immunoglobulin Production
Cell Adhesion
Regulation Of Endocytosis
Regulation Of B Cell Proliferation
B Cell Activation
Regulation Of Immune Response
Negative Regulation Of Calcium-mediated Signaling
Negative Regulation Of B Cell Receptor Signaling Pathway
Pathways
Reduction of cytosolic Ca++ levels
Ion homeostasis
Ion transport by P-type ATPases
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
CD22 mediated BCR regulation
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Halothane
Desflurane
Epratuzumab
Inotuzumab ozogamicin
Moxetumomab Pasudotox
Diseases
GWAS
Breast size (
22747683
)
Composite immunoglobulin trait (IgA x IgG/IgM) (
28628107
)
Hemoglobin (
32888494
)
Hemoglobin concentration (
27863252
)
Hemoglobin levels (
32327693
)
Immature fraction of reticulocytes (
32888494
)
Lymphocyte counts (
32888494
27863252
)
Malaria (
22895189
31844061
)
Mean corpuscular hemoglobin concentration (
23263863
32888494
28453575
27863252
)
Mean corpuscular volume (
32888494
27863252
)
Monocyte count (
32888494
)
Obstructive sleep apnea (average oxygen saturation during sleep) (
26977737
)
Plateletcrit (
32888494
)
Red blood cell count (
32888494
)
Red cell distribution width (
32888494
27863252
28957414
)
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
White blood cell count (
32888494
)
Red cell distribution width (
32888494
)
Interacting Genes
11 interacting genes:
CASK
CD22
DLG1
DLG2
DLG3
DLG4
ERBIN
NOS1
PPP3CA
RASSF1
SRC
20 interacting genes:
ANKRD46
AP2M1
ATP2B4
CD19
GRB2
HP
IGHM
INPP5D
LCP2
LYN
MTDH
NTAQ1
PIK3R1
PLCG1
PTPN6
PTPRC
SHC1
ST6GAL1
SYK
TMEM140
Entrez ID
493
933
HPRD ID
00159
00114
Ensembl ID
ENSG00000058668
ENSG00000012124
Uniprot IDs
A0A024R968
P23634
P20273
Q0EAF5
PDB IDs
1CFF
2KNE
5VKJ
5VKM
5VL3
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?