CNOT2 and GALNT10

Data Source:
BioGRID (two hybrid)

		CNOT2	GALNT10
Description		CCR4-NOT transcription complex subunit 2	polypeptide N-acetylgalactosaminyltransferase 10
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GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane CCR4-NOT Complex CCR4-NOT Core Complex	Golgi Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Transcription Corepressor Binding Transcription Coregulator Activity Poly(A)-specific Ribonuclease Activity Protein Binding	Polypeptide N-acetylgalactosaminyltransferase Activity Carbohydrate Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Nuclear-transcribed MRNA Poly(A) Tail Shortening Trophectodermal Cell Differentiation Regulation Of Transcription By RNA Polymerase II Regulation Of Translation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly Gene Silencing By RNA Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Regulation Of Stem Cell Population Maintenance	Protein O-linked Glycosylation O-glycan Processing Protein Phosphopantetheinylation
Pathways		Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (age of onset) ( 22959728) Diastolic blood pressure ( 27841878) Ovarian cancer ( 30557369) Triglyceride levels ( 32154731)	Autism spectrum disorder or schizophrenia ( 28540026) Behavioural disinhibition (generation interaction) ( 23942779) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 21701570 25673413 23583978) Body mass index (adult) ( 28430825) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Carotid artery intima media thickness (sex interaction) ( 25898001) Childhood body mass index ( 26604143) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Feeling tense ( 29500382) Menarche (age at onset) ( 25231870) Neurociticism ( 29500382) Neurofibrillary tangles ( 31497858) Response to quetiapine in schizophrenia ( 29503163) Schizophrenia ( 28991256 25056061 29483656 30285260) Triglyceride levels ( 32203549)
Interacting Genes		26 interacting genes: ARMC5 BCL6 BEX1 C11orf1 C20orf85 CCHCR1 CNOT1 CNOT3 CNOT4 CNOT8 CSTF2 DDB1 GALNT10 GCSAM GPS1 GPS2 HSF2BP MTFR1L NCOR1 NCOR2 PRR35 PSMB4 RACK1 TBX2 TEKT3 ZFHX3	3 interacting genes: CNOT2 MUC1 MUC7
Entrez ID		4848	55568
HPRD ID		05367	12157
Ensembl ID		ENSG00000111596	ENSG00000164574
Uniprot IDs		A0A024RBD8 B2RDX7 B3KTL6 F8VUB4 F8VV52 Q9NZN8	Q86SR1
PDB IDs		4C0D 4C0F 5FU6 5FU7	2D7I 2D7R
Enriched GO Terms of Interacting Partners?
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