NAP1L2 and PPP3R1

Data Source:
BioGRID (two hybrid)

		NAP1L2	PPP3R1
Description		nucleosome assembly protein 1 like 2	protein phosphatase 3 regulatory subunit B, alpha
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleoplasm Mitochondrion Cytosol Calcineurin Complex Sarcolemma
	Molecular Function	Chromatin Binding Protein Binding Histone Binding	Calcium-dependent Protein Serine/threonine Phosphatase Activity Calcium Ion Binding Protein Binding Calmodulin Binding Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity Cyclosporin A Binding Phosphatase Binding Protein Domain Specific Binding
	Biological Process	Nucleosome Assembly Positive Regulation Of Neuron Differentiation Positive Regulation Of Histone H3-K14 Acetylation Regulation Of Stem Cell Division Positive Regulation Of Histone H3-K9 Acetylation	Protein Dephosphorylation Wnt Signaling Pathway, Calcium Modulating Pathway Calcineurin-NFAT Signaling Cascade Fc-epsilon Receptor Signaling Pathway Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways			Activation of BAD and translocation to mitochondria DARPP-32 events Calcineurin activates NFAT Calcineurin activates NFAT FCERI mediated Ca+2 mobilization Ca2+ pathway CLEC7A (Dectin-1) induces NFAT activation
Drugs			Myristic acid Voclosporin
Diseases
GWAS		Bipolar disorder ( 31043756)	General cognitive ability ( 29844566) Height ( 25282103) Intelligence (MTAG) ( 29326435) Schizophrenia ( 30285260) Urinary potassium excretion ( 31409800)
Interacting Genes		13 interacting genes: CCDC146 CCDC185 DMAP1 FAM81A KLHL2 MED30 NAP1L1 NAP1L5 PPP1R13B PPP3R1 SCNM1 SH3BP5 SP110	10 interacting genes: CABP1 CABP2 CABP5 CHRNA6 MAP3K5 NAP1L2 NFATC1 NFATC2 PPP3CA PPP3CC
Entrez ID		4674	5534
HPRD ID		02066	03195
Ensembl ID		ENSG00000186462	ENSG00000221823
Uniprot IDs		Q9ULW6	P63098
PDB IDs			1AUI 1M63 1MF8 2P6B 3LL8 4F0Z 4OR9 4ORA 4ORC 5SVE 6NUC 6NUF 6NUU
Enriched GO Terms of Interacting Partners?
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