PPP3R1 and CABP5

Data Source:
BioGRID (pull down)

		PPP3R1	CABP5
Description		protein phosphatase 3 regulatory subunit B, alpha	calcium binding protein 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Cytosol Calcineurin Complex Sarcolemma	Cytosol
	Molecular Function	Calcium-dependent Protein Serine/threonine Phosphatase Activity Calcium Ion Binding Protein Binding Calmodulin Binding Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity Cyclosporin A Binding Phosphatase Binding Protein Domain Specific Binding	Calcium Ion Binding Protein Binding
	Biological Process	Protein Dephosphorylation Wnt Signaling Pathway, Calcium Modulating Pathway Calcineurin-NFAT Signaling Cascade Fc-epsilon Receptor Signaling Pathway Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway	Signal Transduction
Pathways		Activation of BAD and translocation to mitochondria DARPP-32 events Calcineurin activates NFAT Calcineurin activates NFAT FCERI mediated Ca+2 mobilization Ca2+ pathway CLEC7A (Dectin-1) induces NFAT activation
Drugs		Myristic acid Voclosporin
Diseases
GWAS		General cognitive ability ( 29844566) Height ( 25282103) Intelligence (MTAG) ( 29326435) Schizophrenia ( 30285260) Urinary potassium excretion ( 31409800)	Body mass index ( 31888951) Obesity (extreme) ( 31888951) Refractive error ( 32231278) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		10 interacting genes: CABP1 CABP2 CABP5 CHRNA6 MAP3K5 NAP1L2 NFATC1 NFATC2 PPP3CA PPP3CC	36 interacting genes: ACOT11 ANKRD55 CADPS CEP76 CT55 DDIT4L IKZF3 INCA1 LNX1 LZTS2 MEI4 NME4 PAX4 PPP3R1 PSMA1 REL SDCBP TCF4 TLE5 TNNI1 VPS52 ZBTB42 ZC2HC1C ZKSCAN4 ZNF169 ZNF223 ZNF229 ZNF280A ZNF398 ZNF474 ZNF559 ZNF620 ZNF664 ZNF669 ZNF835 ZNF844
Entrez ID		5534	56344
HPRD ID		03195	09537
Ensembl ID		ENSG00000221823	ENSG00000105507
Uniprot IDs		P63098	Q9NP86
PDB IDs		1AUI 1M63 1MF8 2P6B 3LL8 4F0Z 4OR9 4ORA 4ORC 5SVE 6NUC 6NUF 6NUU
Enriched GO Terms of Interacting Partners?
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