MYC and TSC1

  • Data Source:
  • BioGRID (affinity chromatography technology, fluorescent resonance energy transfer)

MYC

TSC1

Description MYC proto-oncogene, bHLH transcription factor TSC complex subunit 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 178 interacting genes: ACTL6A AKT1 APP ARAF ARNT ATAD2 AURKA AXIN1 BCL2 BIN1 BRCA1 BRD3 BTRC CALM1 CBLC CCAR2 CCNE1 CCNT1 CDC6 CDC73 CDCA7L CDK1 CDK4 CDK6 CDK8 CDK9 CDKN1B CDKN2A CDKN2B CDKN2C CEBPA CEBPB CEP57 CIP2A CREBBP CSNK2A1 CSNK2A2 DACH1 DNMT3A EFNB1 ELF3 EP300 EP400 EPHA2 ERBB2 FBXO8 FBXW7 FBXW8 FGFR4 FZR1 GCN1 GLIS1 GLIS2 GPX2 GRM1 GSK3A GSK3B GTF2F1 GTF2F2 GTF2I HGF HIF1A HSP90AA1 ING4 KAT2A KAT2B KAT5 KDELR2 KDM1A KIDINS220 LATS2 LDOC1 MAP2K1 MAP2K5 MAPK1 MAPK14 MAPK3 MAPK7 MAPK8 MAX MDM2 MED1 MED16 MEN1 MET MLH1 MOK MSH2 MXD1 MXI1 MYCBP MYCBP2 NDRG1 NEK11 NF2 NFIC NFYB NFYC NMI NONO NOTCH3 NSD3 NUCB1 PAK2 PARP10 PDGFRA PFDN5 PIK3CA PLAU PLK1 PML PPP2CA PRDX1 PSMC3 PTEN RAF1 RASSF1 RB1 RBL1 RELA RIOX2 RUVBL1 RUVBL2 SAP130 SENP2 SF3B1 SKP1 SKP2 SMAD2 SMAD3 SMARCA2 SMARCA4 SMARCB1 SMARCC1 SNIP1 SNRNP70 SOX3 SOX4 SP1 SPAG9 STK11 SUPT3H TADA2A TAF12 TAF1B TAF9 TBP TEAD2 TERT TFAP2A TFAP2B TIAM1 TONSL TP53 TP73 TRIM55 TRIM6 TRIM63 TRRAP TSC1 TUBA1A TUBA1B TUBA3C TUBA4A TUBA8 UBB USP2 USP22 USP36 USP37 USP7 VDR WT1 YAF2 YBX1 YY1 ZBTB17 ZNF281 99 interacting genes: AKT1 APPL2 AQP1 ARAF ARID5A ATXN1 AURKA BAG3 BECN1 C1orf94 CCDC120 CCL28 CCNB1 CCND2 CCNE1 CDK1 CDK4 CDK6 CDKN2A CDKN2B CHCHD2 CSTF2 DMRT3 DOK5 ENKD1 EZR FAM110A FAM222B FGFR4 FOXH1 FRS3 GLIS2 GPANK1 HOXC8 HR HSH2D IGFN1 IKBKB KAT2A KDM1A LATS2 LENG1 LMO2 MAP2K5 MAPK14 MSN MYC MYLIP MYOZ3 NEFL NF2 PATL1 PATZ1 PITX1 PLK1 PLK2 POGZ POU6F2 PPP1R18 PPP1R32 PRMT6 RASSF1 RBPMS RDX RHEB RIN1 RIN3 SAMD11 SAMD7 SH2D2A SHC3 SMG9 SOX4 SPAG8 SUOX TBC1D7 TBX6 TCF7L2 TFAP2D TLE5 TNS2 TSC2 TSGA10IP TSHZ3 VENTX VEZF1 VGLL3 VPS37C YPEL3 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ ZIC1 ZNF417 ZNF587 ZNF765
Entrez ID 4609 7248
HPRD ID 01818 05594
Ensembl ID ENSG00000136997 ENSG00000165699
Uniprot IDs P01106 A0A2R8Y5S3 Q32NF0 Q86WV8 Q92574 X5D9D2
PDB IDs 1A93 1EE4 1MV0 1NKP 2A93 2OR9 4Y7R 5I4Z 5I50 6C4U 6E16 6E24 6G6J 6G6K 6G6L 4Z6Y 5EJC
Enriched GO Terms of Interacting Partners?
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