TSC1 and MYLIP

  • Data Source:
  • BioGRID (two hybrid)

TSC1

MYLIP

Description TSC complex subunit 1 myosin regulatory light chain interacting protein
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein B levels ( 32203549)
  • Asthma exacerbations in inhaled corticosteroid treatment ( 30697902)
  • Cholesterol, total ( 24097068)
  • Diisocyanate-induced asthma ( 25918132)
  • Femoral neck bone mineral density ( 30172743)
  • LDL cholesterol ( 24097068 20864672 25961943)
  • LDL cholesterol levels ( 32203549 28334899 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Major depressive disorder ( 23377640)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Response to statins (LDL cholesterol change) ( 22331829)
  • Total cholesterol levels ( 28334899)
Interacting Genes 99 interacting genes: AKT1 APPL2 AQP1 ARAF ARID5A ATXN1 AURKA BAG3 BECN1 C1orf94 CCDC120 CCL28 CCNB1 CCND2 CCNE1 CDK1 CDK4 CDK6 CDKN2A CDKN2B CHCHD2 CSTF2 DMRT3 DOK5 ENKD1 EZR FAM110A FAM222B FGFR4 FOXH1 FRS3 GLIS2 GPANK1 HOXC8 HR HSH2D IGFN1 IKBKB KAT2A KDM1A LATS2 LENG1 LMO2 MAP2K5 MAPK14 MSN MYC MYLIP MYOZ3 NEFL NF2 PATL1 PATZ1 PITX1 PLK1 PLK2 POGZ POU6F2 PPP1R18 PPP1R32 PRMT6 RASSF1 RBPMS RDX RHEB RIN1 RIN3 SAMD11 SAMD7 SH2D2A SHC3 SMG9 SOX4 SPAG8 SUOX TBC1D7 TBX6 TCF7L2 TFAP2D TLE5 TNS2 TSC2 TSGA10IP TSHZ3 VENTX VEZF1 VGLL3 VPS37C YPEL3 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ ZIC1 ZNF417 ZNF587 ZNF765 41 interacting genes: ADAMTSL4 AR ARID5A CNPY2 CRK DAPP1 DDIT4L EFHC2 EXOSC5 FAM217B GMCL1 HOOK2 INO80B KANK4 KDM1A LNX2 LRP8 MIPOL1 MTAP MYL12B NHLRC4 NOXA1 NR1D2 PAX9 RASSF5 SCNM1 SDCBP SRPK2 TCEANC TSC1 TSC22D4 UBE2D2 UBE2D3 UBE2D4 UBE2N VLDLR ZBTB16 ZBTB18 ZBTB42 ZNF417 ZNF438
Entrez ID 7248 29116
HPRD ID 05594 17621
Ensembl ID ENSG00000165699 ENSG00000007944
Uniprot IDs A0A2R8Y5S3 Q32NF0 Q86WV8 Q92574 X5D9D2 Q5TIA5 Q8WY64
PDB IDs 4Z6Y 5EJC 2YHN 2YHO 6QLY 6QLZ
Enriched GO Terms of Interacting Partners?
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