MX1 and TRPC7

Data Source:
HPRD (in vivo, in vitro)

		MX1	TRPC7
Description		MX dynamin like GTPase 1	transient receptor potential cation channel subfamily C member 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Postsynaptic Density Microtubule Cytoskeleton Membrane Axon Cytoplasmic Vesicle Nuclear Membrane Mitochondrial Membrane Dendritic Spine Head Perinuclear Region Of Cytoplasm Presynapse Postsynaptic Endocytic Zone Membrane	Nuclear Envelope Cis-Golgi Network Plasma Membrane Integral Component Of Plasma Membrane Cation Channel Complex Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Activity Protein Binding GTP Binding Microtubule Binding Identical Protein Binding	Protein Binding Store-operated Calcium Channel Activity Inositol 1,4,5 Trisphosphate Binding
	Biological Process	Mitochondrial Fission Dynamin Family Protein Polymerization Involved In Mitochondrial Fission Apoptotic Process Defense Response Signal Transduction Response To Virus Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Receptor Internalization Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Regulation Of Synapse Structure Or Activity Defense Response To Virus Type I Interferon Signaling Pathway Membrane Fusion Postsynaptic Neurotransmitter Receptor Internalization	Manganese Ion Transport Single Fertilization Platelet Activation Regulation Of Cytosolic Calcium Ion Concentration Calcium Ion Transmembrane Transport
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling	Effects of PIP2 hydrolysis Elevation of cytosolic Ca2+ levels TRP channels Role of second messengers in netrin-1 signaling
Drugs
Diseases
GWAS			Body fat percentage ( 31752434) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) Sleep duration (short sleep) ( 30846698)
Interacting Genes		41 interacting genes: ACTB ADRM1 APP BLM BRD7 C7orf25 CAB39L CASP8AP2 CBX4 CHD3 DAXX EPM2AIP1 FANCA GMEB1 HMGXB4 KIF26B KLHL35 LRRC4B MCCD1 PIAS1 PIAS2 PLRG1 PSD3 RELA SIAH1 SIRPA SLC25A3 SP100 TDG TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBA1A TUBB ZBTB16 ZCCHC12 ZNF251 ZNF623	4 interacting genes: ITPR3 MX1 TRPC3 TRPC6
Entrez ID		4599	57113
HPRD ID		00919	18228
Ensembl ID		ENSG00000157601	ENSG00000069018
Uniprot IDs		P20591	Q9HCX4
PDB IDs		3LJB 3SZR 3ZYS 4P4S 4P4T 4P4U 5GTM
Enriched GO Terms of Interacting Partners?
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