MX1 and MCCD1

Data Source:
BioGRID (two hybrid)

		MX1	MCCD1
Description		MX dynamin like GTPase 1	mitochondrial coiled-coil domain 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Postsynaptic Density Microtubule Cytoskeleton Membrane Axon Cytoplasmic Vesicle Nuclear Membrane Mitochondrial Membrane Dendritic Spine Head Perinuclear Region Of Cytoplasm Presynapse Postsynaptic Endocytic Zone Membrane	Mitochondrion
	Molecular Function	GTPase Activity Protein Binding GTP Binding Microtubule Binding Identical Protein Binding	Protein Binding
	Biological Process	Mitochondrial Fission Dynamin Family Protein Polymerization Involved In Mitochondrial Fission Apoptotic Process Defense Response Signal Transduction Response To Virus Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Receptor Internalization Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Regulation Of Synapse Structure Or Activity Defense Response To Virus Type I Interferon Signaling Pathway Membrane Fusion Postsynaptic Neurotransmitter Receptor Internalization
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling
Drugs
Diseases
GWAS			AIDS progression ( 19115949) Asthma ( 31619474 29273806) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Cervical cancer ( 28806749) Inflammatory bowel disease ( 28067908) Lymphocyte counts ( 32888494) Malaria ( 31844061) Monocyte count ( 32888494) Ulcerative colitis ( 28067908)
Interacting Genes		41 interacting genes: ACTB ADRM1 APP BLM BRD7 C7orf25 CAB39L CASP8AP2 CBX4 CHD3 DAXX EPM2AIP1 FANCA GMEB1 HMGXB4 KIF26B KLHL35 LRRC4B MCCD1 PIAS1 PIAS2 PLRG1 PSD3 RELA SIAH1 SIRPA SLC25A3 SP100 TDG TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBA1A TUBB ZBTB16 ZCCHC12 ZNF251 ZNF623	26 interacting genes: BEX3 BFSP2 CAB39 COX5B FNDC3B KANK2 KRT26 KYNU LMO4 LSM1 MEIS2 MGAT5B MKRN3 MX1 MYL7 P4HA3 PIH1D2 PPP1R16A PRR35 QARS1 RIPPLY1 USHBP1 USP20 ZNF417 ZNF587 ZNF765
Entrez ID		4599	401250
HPRD ID		00919	17470
Ensembl ID		ENSG00000157601	ENSG00000204511
Uniprot IDs		P20591	A0A1U9X802 P59942
PDB IDs		3LJB 3SZR 3ZYS 4P4S 4P4T 4P4U 5GTM
Enriched GO Terms of Interacting Partners?
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