MT-ND1 and FAT1

Data Source:
BioGRID (two hybrid)

		MT-ND1	FAT1
Description		NADH dehydrogenase subunit 1	FAT atypical cadherin 1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Integral Component Of Membrane Dendrite Mitochondrial Membrane Neuronal Cell Body	Nucleus Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	NADH Dehydrogenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity	Calcium Ion Binding Protein Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Response To Organic Cyclic Compound Mitochondrial Respiratory Chain Complex I Assembly Response To Hydroperoxide Response To Drug	Actin Filament Organization Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Establishment Or Maintenance Of Cell Polarity Cell-cell Signaling Anatomical Structure Morphogenesis Cell Migration Cell-cell Adhesion
Pathways		Respiratory electron transport Complex I biogenesis
Drugs		NADH Methoxyflurane Halothane Desflurane Sevoflurane N-Formylmethionine Phenethyl Isothiocyanate
Diseases		Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS			Alzheimer disease and age of onset ( 26830138) Carotid plaque burden ( 28282560) Chronotype ( 26955885) Heel bone mineral density ( 30598549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Macular thickness ( 30535121) Major depressive disorder ( 29317602) Medication use (calcium channel blockers) ( 31015401) Morning vs. evening chronotype ( 26955885) Obesity ( 21552555) PR interval ( 30046033 32439900) Urinary albumin-to-creatinine ratio ( 31630189)
Interacting Genes		12 interacting genes: BARD1 BRCA1 DHDDS FAT1 LIG4 MEOX2 NDUFS7 PAXIP1 RPL13A RPL6 SIRPA TST	12 interacting genes: CLK1 ENAH HOMER1 HOMER3 IGLL1 MT-ND1 NOXA1 SORBS2 TRAF4 TRIM14 UBC VASP
Entrez ID		4535	2195
HPRD ID		08365	02986
Ensembl ID		ENSG00000198888	ENSG00000083857
Uniprot IDs		P03886 U5Z754	Q14517
PDB IDs		5XTC 5XTD
Enriched GO Terms of Interacting Partners?
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