FAT1 and IGLL1

Data Source:
BioGRID (two hybrid)

		FAT1	IGLL1
Description		FAT atypical cadherin 1	immunoglobulin lambda like polypeptide 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion Perinuclear Region Of Cytoplasm Extracellular Exosome	Extracellular Region Endoplasmic Reticulum External Side Of Plasma Membrane Membrane Immunoglobulin Complex, Circulating
	Molecular Function	Calcium Ion Binding Protein Binding	Antigen Binding Protein Binding Immunoglobulin Receptor Binding
	Biological Process	Actin Filament Organization Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Establishment Or Maintenance Of Cell Polarity Cell-cell Signaling Anatomical Structure Morphogenesis Cell Migration Cell-cell Adhesion	Phagocytosis, Recognition Phagocytosis, Engulfment Immune Response Complement Activation, Classical Pathway Defense Response To Bacterium Innate Immune Response B Cell Receptor Signaling Pathway Positive Regulation Of B Cell Activation Leukocyte Migration
Pathways			Cell surface interactions at the vascular wall
Drugs			Copper
Diseases			Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS		Alzheimer disease and age of onset ( 26830138) Carotid plaque burden ( 28282560) Chronotype ( 26955885) Heel bone mineral density ( 30598549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Macular thickness ( 30535121) Major depressive disorder ( 29317602) Medication use (calcium channel blockers) ( 31015401) Morning vs. evening chronotype ( 26955885) Obesity ( 21552555) PR interval ( 30046033 32439900) Urinary albumin-to-creatinine ratio ( 31630189)	Blood protein levels ( 30072576 29875488) Height ( 18391951) HOMA-B (corrected for HOMA-IR) ( 30369944) Migraine ( 21448238) Peripheral artery disease ( 25009551)
Interacting Genes		12 interacting genes: CLK1 ENAH HOMER1 HOMER3 IGLL1 MT-ND1 NOXA1 SORBS2 TRAF4 TRIM14 UBC VASP	6 interacting genes: FAM25A FAM25C FAM25G FAT1 MYOC UBQLN2
Entrez ID		2195	3543
HPRD ID		02986	00905
Ensembl ID		ENSG00000083857	ENSG00000128322
Uniprot IDs		Q14517	P15814
PDB IDs			2H32 2H3N 2LKQ
Enriched GO Terms of Interacting Partners?
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