ASGR1 and SPAG4

Data Source:
BioGRID (two hybrid)

		ASGR1	SPAG4
Description		asialoglycoprotein receptor 1	sperm associated antigen 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane	Nuclear Envelope Nuclear Inner Membrane Cytoplasm Cytoskeleton Integral Component Of Membrane Motile Cilium Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding Metal Ion Binding	Structural Molecule Activity Protein Binding Protein-membrane Adaptor Activity
	Biological Process	Receptor-mediated Endocytosis Viral Process Protein N-linked Glycosylation Via Asparagine Cellular Response To Extracellular Stimulus	Nuclear Envelope Organization Spermatogenesis Cell Differentiation
Pathways		Asparagine N-linked glycosylation
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 22001757) Low density lipoprotein cholesterol levels ( 32154731) Medication use (HMG CoA reductase inhibitors) ( 31015401) Serum alkaline phosphatase levels ( 31666285 29403010)	Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		43 interacting genes: AHNAK2 AMIGO1 APH1A APP ASGR2 ATP1B4 BLCAP CERS2 CLDN7 CLEC4G CPLX4 CREB3L1 CYB5R3 DHFR ERGIC3 FAM209A FCGR1A FNDC9 GPX8 HIBADH HIVEP1 HSP90AA1 HSP90B1 IGFBP5 KIR2DL3 LAMTOR5 LEUTX LMNA MCEMP1 NEMP1 NLK PDZK1IP1 RBBP6 RNF19B SAR1A SLC10A1 SLC35C2 SPAG4 SUSD3 TG TMX2 VKORC1 VSIR	24 interacting genes: ABHD16A ASGR1 BMP10 CSGALNACT1 ERMP1 GOSR2 IGFBP5 MS4A13 NRM ODF1 PAXIP1 PGA4 PLN PTPN9 RUSF1 SCAMP4 SCD SEC22A SUN5 TMEM187 TMEM60 TNMD TRARG1 TSPO2
Entrez ID		432	6676
HPRD ID		00151	04330
Ensembl ID		ENSG00000141505	ENSG00000061656
Uniprot IDs		P07306 Q6FGQ5	Q9NPE6
PDB IDs		1DV8 5JPV 5JQ1
Enriched GO Terms of Interacting Partners?
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