MEP1B and OS9

Data Source:
HPRD (two hybrid, in vitro)

		MEP1B	OS9
Description		meprin A subunit beta	OS9 endoplasmic reticulum lectin
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GO Annotations	Cellular Component	Extracellular Region Integral Component Of Plasma Membrane Meprin A Complex	Hrd1p Ubiquitin Ligase Complex Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Metalloendopeptidase Activity Protein Binding Zinc Ion Binding Identical Protein Binding	Protease Binding Protein Binding Carbohydrate Binding
	Biological Process	Proteolysis Inflammatory Response Toxin Transport	Ubiquitin-dependent Protein Catabolic Process Protein Targeting Protein Retention In ER Lumen Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Response To Endoplasmic Reticulum Stress Transmembrane Transport Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Endoplasmic Reticulum Mannose Trimming
Pathways			ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) TRAIL levels ( 27989323)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Multiple sclerosis ( 31604244) Rheumatoid arthritis (ACPA-positive) ( 24532676)
Interacting Genes		12 interacting genes: CCK FN1 GAST GCG GRP MEP1A NPY OS9 PRKACA PRKCD PYY SCT	19 interacting genes: ACVR1B CPNE6 CREB3 DCSTAMP DYSF EGLN1 EGLN3 EIF6 FOXM1 HIF1A HSP90B1 LINC00839 MEP1B RBX1 SMAD2 SNRPD2 SREBF2 TRPV4 ZNF512B
Entrez ID		4225	10956
HPRD ID		02667	17804
Ensembl ID		ENSG00000141434	ENSG00000135506
Uniprot IDs		J3QKX5 Q16820	Q13438
PDB IDs		4GWM 4GWN	3AIH
Enriched GO Terms of Interacting Partners?
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