MEIS2 and FAM136A

Data Source:
BioGRID (two hybrid)

		MEIS2	FAM136A
Description		Meis homeobox 2	family with sequence similarity 136 member A
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Perinuclear Region Of Cytoplasm	Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Positive Regulation Of Cell Population Proliferation Visual Learning Response To Mechanical Stimulus Embryonic Pattern Specification Animal Organ Morphogenesis Pancreas Development Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Response To Growth Factor Positive Regulation Of Cardiac Muscle Myoblast Proliferation
Pathways
Drugs
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Hyperactive-impulsive symptoms ( 18821565) Intraocular pressure ( 24002674) Major depressive disorder ( 27479909) Post bronchodilator FEV1 in COPD ( 26634245) Postprandial triglyceride response ( 32603185) Response to antipsychotic treatment ( 20195266) Restless legs syndrome ( 29029846) Voxel-wise structural brain imaging measurements in Alzheimerâ€™s disease ( 30584014)	Acne (severe) ( 24927181) LDL cholesterol ( 30275531) Male-pattern baldness ( 28196072) Metabolite levels ( 23823483) Response to citalopram or escitalopram in depression ( 27622933) Total cholesterol levels ( 30275531)
Interacting Genes		49 interacting genes: ADRA2C ANTKMT ANXA1 APP ARNT2 BPIFA1 C1orf94 C9orf24 CARTPT CCDC196 CTAG1A CTAG1B DGCR6 FAM136A FAM168A HOXA13 HOXA9 IGFBP6 ITGB3BP KRTAP10-8 KRTAP11-1 KRTAP13-1 KRTAP19-2 KRTAP19-6 KRTAP22-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 MCCD1 NDUFB7 NOTO NUP58 OIP5 OSGIN1 PBX1 PBX4 POU2AF1 POU6F2 PTK6 RBPMS RUSC1 SCT SQSTM1 TBX2 TIMM10B TRIM25 TRIM42 VGLL1 ZNHIT3	11 interacting genes: ANKRD11 DPY30 MAGEB4 MBD3 MEIS2 NTAQ1 P4HA3 PSMB1 RUNX1T1 SMARCD1 TTC19
Entrez ID		4212	84908
HPRD ID		03443	07866
Ensembl ID		ENSG00000134138	ENSG00000035141
Uniprot IDs		A0A024R9L4 B3KP81 B3KPD8 B7Z6F6 O14770	B0AZT6 E7EQY1 Q96C01
PDB IDs		3K2A 4XRM 5BNG 5EG0
Enriched GO Terms of Interacting Partners?
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