MEIS2 and NUP58

Data Source:
BioGRID (two hybrid)

		MEIS2	NUP58
Description		Meis homeobox 2	nucleoporin 58
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GO Annotations	Cellular Component	Chromatin Nucleus Perinuclear Region Of Cytoplasm	Nuclear Envelope Nuclear Pore Nuclear Membrane Host Cell
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Nuclear Localization Sequence Binding Structural Constituent Of Nuclear Pore Identical Protein Binding Protein-containing Complex Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Positive Regulation Of Cell Population Proliferation Visual Learning Response To Mechanical Stimulus Embryonic Pattern Specification Animal Organ Morphogenesis Pancreas Development Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Response To Growth Factor Positive Regulation Of Cardiac Muscle Myoblast Proliferation	Regulation Of Glycolytic Process MRNA Export From Nucleus TRNA Export From Nucleus Viral Process Protein Sumoylation Viral Transcription Regulation Of Protein Import Into Nucleus Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat
Pathways
Drugs
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Hyperactive-impulsive symptoms ( 18821565) Intraocular pressure ( 24002674) Major depressive disorder ( 27479909) Post bronchodilator FEV1 in COPD ( 26634245) Postprandial triglyceride response ( 32603185) Response to antipsychotic treatment ( 20195266) Restless legs syndrome ( 29029846) Voxel-wise structural brain imaging measurements in Alzheimerâ€™s disease ( 30584014)
Interacting Genes		49 interacting genes: ADRA2C ANTKMT ANXA1 APP ARNT2 BPIFA1 C1orf94 C9orf24 CARTPT CCDC196 CTAG1A CTAG1B DGCR6 FAM136A FAM168A HOXA13 HOXA9 IGFBP6 ITGB3BP KRTAP10-8 KRTAP11-1 KRTAP13-1 KRTAP19-2 KRTAP19-6 KRTAP22-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 MCCD1 NDUFB7 NOTO NUP58 OIP5 OSGIN1 PBX1 PBX4 POU2AF1 POU6F2 PTK6 RBPMS RUSC1 SCT SQSTM1 TBX2 TIMM10B TRIM25 TRIM42 VGLL1 ZNHIT3	19 interacting genes: ABI3 AGR2 APC COG3 COG6 HTT KRT27 KRT28 KRT33B MAPK3 MEIS2 MIS18A NUP62 PKNOX1 PKNOX2 TRAF1 TRIM54 UBQLN1 UBQLN2
Entrez ID		4212	9818
HPRD ID		03443	06355
Ensembl ID		ENSG00000134138	ENSG00000139496
Uniprot IDs		A0A024R9L4 B3KP81 B3KPD8 B7Z6F6 O14770	Q9BVL2
PDB IDs		3K2A 4XRM 5BNG 5EG0	4JO7 4JO9 4JQ5 5IJN 5IJO
Enriched GO Terms of Interacting Partners?
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