ARVCF and CDH15

Data Source:
BioGRID (pull down)
HPRD (in vivo, two hybrid, in vitro)

		ARVCF	CDH15
Description		ARVCF delta catenin family member	cadherin 15
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Nucleus Cytoplasm Plasma Membrane Adherens Junction	Golgi Apparatus Plasma Membrane Caveola Integral Component Of Membrane Catenin Complex Neuromuscular Junction Extracellular Exosome
	Molecular Function	Protein Binding Cadherin Binding	Calcium Ion Binding Protein Binding Cadherin Binding
	Biological Process	Cell-cell Junction Assembly Cell Adhesion Multicellular Organism Development Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell-cell Adhesion	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Adherens Junction Organization Positive Regulation Of Muscle Cell Differentiation Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Pathways			Adherens junctions interactions Myogenesis Myogenesis
Drugs
Diseases		Classic complement pathway component defects, including the following eight diseases: C1q alpha-chain deficiency; C1q beta-chain deficiency; C1q gamma-chain deficiency; C1r deficiency; C1s deficiency; C2 deficiency; C3 deficiency; C4 deficiency	Non-syndromic autosomal dominant mental retardation
GWAS		Central corneal thickness ( 32528159 29760442) Lymphocyte counts ( 32888494 27863252) Medication use (antihypertensives) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Monocyte count ( 32888494 27863252) Neutrophil count ( 32888494) Platelet count ( 22139419 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Pulse pressure ( 28135244 27841878 28739976 30487518 30578418) Systolic blood pressure ( 27841878 30487518 30578418) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) White blood cell count ( 32888494 27863252)
Interacting Genes		6 interacting genes: CDH1 CDH15 CDH2 ERBIN LNX1 TJP1	12 interacting genes: ARVCF BOC CDH7 CDH9 CDON CTNNA1 CTNNB1 GNA12 JUP SGTA SGTB UBQLN2
Entrez ID		421	1013
HPRD ID		03778	00225
Ensembl ID		ENSG00000099889	ENSG00000129910
Uniprot IDs		C9JJX6 E9PDC3 O00192	P55291
PDB IDs
Enriched GO Terms of Interacting Partners?
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