CDH15 and CDON

Data Source:
HPRD (in vivo)

		CDH15	CDON
Description		cadherin 15	cell adhesion associated, oncogene regulated
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Caveola Integral Component Of Membrane Catenin Complex Neuromuscular Junction Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Collagen-containing Extracellular Matrix
	Molecular Function	Calcium Ion Binding Protein Binding Cadherin Binding	Protein Binding
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Adherens Junction Organization Positive Regulation Of Muscle Cell Differentiation Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules	Cell Fate Specification Positive Regulation Of Protein Phosphorylation Lens Development In Camera-type Eye Cell Adhesion Smoothened Signaling Pathway Myoblast Fusion Anterior/posterior Pattern Specification Embryonic Body Morphogenesis Skeletal Muscle Satellite Cell Differentiation Cerebral Cortex Development Regulation Of Protein Binding Positive Regulation Of MAPK Cascade Positive Regulation Of Myoblast Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Muscle Cell Differentiation Embryonic Retina Morphogenesis In Camera-type Eye Positive Regulation Of Neural Precursor Cell Proliferation
Pathways		Adherens junctions interactions Myogenesis Myogenesis	Myogenesis Myogenesis Ligand-receptor interactions Activation of SMO
Drugs
Diseases		Non-syndromic autosomal dominant mental retardation
GWAS			Alzheimer's disease (late onset) ( 22881374) Blood protein levels ( 30072576 29875488 28240269) Cerebral white matter volume ( 31530798) Height ( 31562340) Lung function (FEV1) ( 28166213) Mild to moderate chronic kidney disease ( 31178898) Primary tooth development (time to first tooth eruption) ( 23704328) Systolic blood pressure x educational attainment (some college) interaction (2df) ( 32372009) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		12 interacting genes: ARVCF BOC CDH7 CDH9 CDON CTNNA1 CTNNB1 GNA12 JUP SGTA SGTB UBQLN2	5 interacting genes: ABL1 BOC CDH15 CDH2 CTNNB1
Entrez ID		1013	50937
HPRD ID		00225	16372
Ensembl ID		ENSG00000129910	ENSG00000064309
Uniprot IDs		P55291	Q4KMG0
PDB IDs			3D1M 3N1F 3N1Q
Enriched GO Terms of Interacting Partners?
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