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MCM7 and DNAAF6
Data Source:
BioGRID
(two hybrid)
MCM7
DNAAF6
Description
minichromosome maintenance complex component 7
dynein axonemal assembly factor 6
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Chromatin
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Membrane
MCM Complex
CMG Complex
Cytoplasm
Trans-Golgi Network
Molecular Function
DNA Binding
DNA Helicase Activity
DNA Replication Origin Binding
Single-stranded DNA Binding
Protein Binding
ATP Binding
Single-stranded 3'-5' DNA Helicase Activity
Protein Binding
Dynein Intermediate Chain Binding
Chaperone Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Double-strand Break Repair Via Break-induced Replication
DNA Replication
Pre-replicative Complex Assembly Involved In Nuclear Cell Cycle DNA Replication
DNA Unwinding Involved In DNA Replication
DNA Replication Initiation
DNA Strand Elongation Involved In DNA Replication
Cellular Response To DNA Damage Stimulus
Cell Population Proliferation
Regulation Of Phosphorylation
Response To Drug
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Xenobiotic Stimulus
Cilium Movement
Flagellated Sperm Motility
Outer Dynein Arm Assembly
Inner Dynein Arm Assembly
Axonemal Dynein Complex Assembly
Pathways
Activation of ATR in response to replication stress
Unwinding of DNA
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex
Switching of origins to a post-replicative state
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Refractive error (
32231278
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
77 interacting genes:
ABI2
AK8
APP
ASB8
C8orf34
CCDC102B
CCND1
CCNH
CDC42
CDC45
CDC6
CDC7
CDK7
CDKN1B
CEP68
CHEK1
COG6
CRLS1
DBF4
DNAAF6
DUX4
ELOC
ESCO2
FHL2
GOLGA2
H3-4
HIF1A
IKBKG
IKZF3
INTS6
KIFC3
LINC01554
LNX2
MAGEA6
MBIP
MCM10
MCM2
MCM3
MCM4
MCM5
MCM6
MCM8
MCMBP
MEOX2
MIPOL1
MNAT1
NAB2
NFKBIA
ORC1
ORC2
ORC3
ORC4
ORC5
ORC6
PLK1
PNMA1
RAD17
RB1
RBL1
RBL2
RBM8A
RBPMS
RINT1
RPA1
SMC1A
SNTA1
SP2
SSX2IP
TFIP11
TREX1
TRIM27
TRIM54
TRIM55
TRIM63
UBE3A
UBQLN1
USHBP1
16 interacting genes:
ARID4B
BTAF1
CCAR1
CDKL3
GAS2L2
KAT5
KIF13A
MCM7
P2RX4
PID1
POLDIP2
PRKAA2
QRICH1
RNF39
TSEN15
YAF2
Entrez ID
4176
139212
HPRD ID
01154
06650
Ensembl ID
ENSG00000166508
ENSG00000080572
Uniprot IDs
A0A0S2Z4A5
C6EMX8
P33993
Q9NQM4
PDB IDs
6XTX
6XTY
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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