MCM3 and MCMBP

Data Source:
BioGRID (affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology)

		MCM3	MCMBP
Description		minichromosome maintenance complex component 3	minichromosome maintenance complex binding protein
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Alpha DNA Polymerase:primase Complex Nucleolus Centrosome Membrane MCM Complex Perinuclear Region Of Cytoplasm CMG Complex	Nucleus Nucleoplasm Cytosol Cell Junction MCM Complex
	Molecular Function	DNA Binding DNA Helicase Activity DNA Replication Origin Binding Single-stranded DNA Binding Protein Binding ATP Binding	Chromatin Binding Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Double-strand Break Repair Via Break-induced Replication DNA Replication Pre-replicative Complex Assembly Involved In Nuclear Cell Cycle DNA Replication DNA Replication Initiation DNA Strand Elongation Involved In DNA Replication DNA Duplex Unwinding Mitotic DNA Replication Initiation	DNA-dependent DNA Replication Sister Chromatid Cohesion Cell Division
Pathways		Activation of ATR in response to replication stress Unwinding of DNA Assembly of the pre-replicative complex Orc1 removal from chromatin Activation of the pre-replicative complex Switching of origins to a post-replicative state
Drugs
Diseases
GWAS			Body size at age 10 ( 32376654) Height ( 28552196)
Interacting Genes		36 interacting genes: CCNE1 CDC45 CDC5L CDC6 CDC7 CDK2 CSNK2A1 DBF4 EP300 HAUS1 KEAP1 LZTR1 MAPK6 MCM10 MCM2 MCM3AP MCM4 MCM5 MCM6 MCM7 MCMBP ORC2 ORC4 ORC5 PLK1 POLR2A PPP2R1A PPP2R1B PTEN RAD52 STAT1 SUMO2 SUPT16H SYF2 TRIM28 YWHAQ	15 interacting genes: ASL DBF4 DDIT3 FKBP5 KEAP1 MCM3 MCM4 MCM5 MCM6 MCM7 PRTFDC1 RWDD2A SNW1 USP7 ZNF474
Entrez ID		4172	79892
HPRD ID		04072	07624
Ensembl ID		ENSG00000112118	ENSG00000197771
Uniprot IDs		A0A0S2Z4T1 A0A499FHX9 B4DUQ9 P25205	A0A0S2Z5P5 Q9BTE3
PDB IDs		6XTX 6XTY	4KG9
Enriched GO Terms of Interacting Partners?
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