MXD1 and PRAM1

Data Source:
HPRD (in vivo)

		MXD1	PRAM1
Description		MAX dimerization protein 1	PML-RARA regulated adaptor molecule 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Mitochondrion Cytosol	Plasma Membrane Protein-containing Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity	Protein Binding Lipid Binding Protein Kinase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Integrin-mediated Signaling Pathway Regulation Of Neutrophil Degranulation T Cell Receptor Signaling Pathway Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Carotid plaque burden (smoking interaction) ( 24954085) High light scatter reticulocyte count ( 32888494 27863252) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494 27863252) Red cell distribution width ( 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Coronary artery disease ( 29212778) Height ( 18391951)
Interacting Genes		18 interacting genes: AKT1 APP CD2 HDAC1 HDAC2 MAX MLX MYC MYCL MYCN PML PRAM1 RPS6KA1 RPS6KB1 SAP30 SIN3A SIN3B SMC3	25 interacting genes: A2M ABI2 APOE APP BCAR1 CCDC57 CDC37 FXR1 FXR2 GOLGA2 KRT40 LCP2 LYN MAST1 MXD1 NEDD9 NEK6 PSEN1 RNF32 SH3RF1 SKAP1 SKAP2 TP53BP2 TRIM27 UBE2E2
Entrez ID		4084	84106
HPRD ID		02487	05926
Ensembl ID		ENSG00000059728	ENSG00000133246
Uniprot IDs		B7ZLI7 Q05195	Q96QH2
PDB IDs		1E91 1G1E 1NLW 1PD7 1S5Q
Enriched GO Terms of Interacting Partners?
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