MXD1 and MYCL

Data Source:
HPRD (in vivo, in vitro)

		MXD1	MYCL
Description		MAX dimerization protein 1	MYCL proto-oncogene, bHLH transcription factor
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Mitochondrion Cytosol	Chromatin Nucleoplasm Chromosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Regulation Of Inner Ear Auditory Receptor Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Carotid plaque burden (smoking interaction) ( 24954085) High light scatter reticulocyte count ( 32888494 27863252) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494 27863252) Red cell distribution width ( 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		18 interacting genes: AKT1 APP CD2 HDAC1 HDAC2 MAX MLX MYC MYCL MYCN PML PRAM1 RPS6KA1 RPS6KB1 SAP30 SIN3A SIN3B SMC3	6 interacting genes: CATSPER1 CCNK MAX MXD1 OTUD6A PRKAA2
Entrez ID		4084	4610
HPRD ID		02487	01279
Ensembl ID		ENSG00000059728	ENSG00000116990
Uniprot IDs		B7ZLI7 Q05195	P12524
PDB IDs		1E91 1G1E 1NLW 1PD7 1S5Q
Enriched GO Terms of Interacting Partners?
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