MIR98 and CPSF1

Data Source:
BioGRID (unspecified method)

		MIR98	CPSF1
Description		microRNA 98	cleavage and polyadenylation specific factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Nucleus Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	Protein Binding Enzyme Binding MRNA 3'-UTR AU-rich Region Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Interleukin-1 Beta Production Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-6 Production Negative Regulation Of Interleukin-8 Production Negative Regulation Of Tumor Necrosis Factor Production Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Neuron Apoptotic Process Interleukin-6-mediated Signaling Pathway Negative Regulation Of Interleukin-6-mediated Signaling Pathway Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of Cytokine Production Involved In Inflammatory Response Cellular Response To Amyloid-beta Negative Regulation Of Vascular Endothelial Cell Proliferation	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Export From Nucleus MRNA 3'-end Processing Pre-mRNA Cleavage Required For Polyadenylation
Pathways			Transport of Mature mRNA Derived from an Intronless Transcript tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)	Educational attainment ( 25201988)
Interacting Genes		77 interacting genes: ADARB1 APOBEC3B ATXN2L C1QBP CPSF1 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 EDC4 EIF2AK2 EPRS1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 NOL6 NONO NUDT16L1 NUFIP2 PDCD11 PLOD1 PTBP1 PTBP3 PUM1 QARS1 RARS1 RBM12B RBM14 RTCB SAFB SF3B1 SF3B2 SF3B3 SFPQ STRBP SYNCRIP TAF15 TRA2A TRA2B TRIM25 TUT4 U2SURP UPF1 YBX1 YBX3 ZFR ZNF346	57 interacting genes: CSTF2T GLIS2 HMOX1 IL7R INCA1 MCM2 MIR1-2 MIR106B MIR107 MIR122 MIR128-2 MIR138-1 MIR138-2 MIR143 MIR155 MIR15A MIR15B MIR16-2 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200C MIR205 MIR206 MIR20B MIR21 MIR214 MIR221 MIR29A MIR31 MIR34A MIR34B MIR7-1 MIR92A1 MIR92A2 MIR98 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7E MIRLET7F2 MIRLET7G MIRLET7I NEDD4 PAPOLA POLR2A PRRC2A REL TAF11 TAF12 TAF13 TAF5 TAF7
Entrez ID		407054	29894
HPRD ID			05823
Ensembl ID		ENSG00000271886	ENSG00000071894
Uniprot IDs			Q10570
PDB IDs			6BLY 6BM0 6DNH 6F9N 6FBS 6FUW 6URG 6URO
Enriched GO Terms of Interacting Partners?
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