MIR98 and ADARB1

Data Source:
BioGRID (unspecified method)

		MIR98	ADARB1
Description		microRNA 98	adenosine deaminase RNA specific B1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Synapse
	Molecular Function	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding Double-stranded RNA Binding Double-stranded RNA Adenosine Deaminase Activity MRNA Binding Protein Binding TRNA-specific Adenosine Deaminase Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Interleukin-1 Beta Production Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-6 Production Negative Regulation Of Interleukin-8 Production Negative Regulation Of Tumor Necrosis Factor Production Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Neuron Apoptotic Process Interleukin-6-mediated Signaling Pathway Negative Regulation Of Interleukin-6-mediated Signaling Pathway Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of Cytokine Production Involved In Inflammatory Response Cellular Response To Amyloid-beta Negative Regulation Of Vascular Endothelial Cell Proliferation	Adenosine To Inosine Editing RNA Processing MRNA Processing Neuromuscular Synaptic Transmission Negative Regulation Of Cell Population Proliferation Base Conversion Or Substitution Editing Facial Nerve Morphogenesis Hypoglossal Nerve Morphogenesis Spinal Cord Ventral Commissure Morphogenesis Negative Regulation Of Cell Migration Multicellular Organism Growth Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Positive Regulation Of Viral Genome Replication Innate Immune Response Neuromuscular Process Controlling Posture Defense Response To Virus Regulation Of Cell Cycle Innervation Muscle Tissue Morphogenesis Motor Behavior Motor Neuron Apoptotic Process
Pathways			C6 deamination of adenosine Formation of editosomes by ADAR proteins
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)	Adult body size ( 32376654) Body mass index ( 28892062 25673413) HDL cholesterol levels ( 32203549) Logical memory (immediate recall) in mild cognitive impairment ( 29274321) Pulmonary function ( 17903307) Triglyceride levels ( 32203549) Type 2 diabetes ( 30130595)
Interacting Genes		77 interacting genes: ADARB1 APOBEC3B ATXN2L C1QBP CPSF1 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 EDC4 EIF2AK2 EPRS1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 NOL6 NONO NUDT16L1 NUFIP2 PDCD11 PLOD1 PTBP1 PTBP3 PUM1 QARS1 RARS1 RBM12B RBM14 RTCB SAFB SF3B1 SF3B2 SF3B3 SFPQ STRBP SYNCRIP TAF15 TRA2A TRA2B TRIM25 TUT4 U2SURP UPF1 YBX1 YBX3 ZFR ZNF346	54 interacting genes: APP EHHADH EIF2AK2 MIR1-1 MIR1-2 MIR106A MIR138-1 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15B MIR16-2 MIR199A2 MIR19B2 MIR200A MIR200B MIR206 MIR221 MIR222 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR363 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR98 MIRLET7A1 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7F1 MIRLET7F2 MIRLET7G NKRF PIN1 PNPT1 PRKRA STAU1 STOX1 STRBP TARBP2 TCEANC UBE2I ZMAT4 ZNF346
Entrez ID		407054	104
HPRD ID			06777
Ensembl ID		ENSG00000271886	ENSG00000197381
Uniprot IDs			P78563
PDB IDs			1ZY7 5ED1 5ED2 5HP2 5HP3 6D06 6VFF
Enriched GO Terms of Interacting Partners?
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