CPSF1 and TAF11

Data Source:
HPRD (in vitro)

		CPSF1	TAF11
Description		cleavage and polyadenylation specific factor 1	TATA-box binding protein associated factor 11
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GO Annotations	Cellular Component	Nucleus Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex	Nucleoplasm Transcription Factor TFIID Complex Golgi Apparatus
	Molecular Function	Protein Binding Enzyme Binding MRNA 3'-UTR AU-rich Region Binding	Transcription Coactivator Activity Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Vitamin D Receptor Binding Thyroid Hormone Receptor Binding Protein Heterodimerization Activity Protein N-terminus Binding
	Biological Process	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Export From Nucleus MRNA 3'-end Processing Pre-mRNA Cleavage Required For Polyadenylation	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter SnRNA Transcription By RNA Polymerase II Positive Regulation By Host Of Viral Transcription Positive Regulation Of Transcription, DNA-templated RNA Polymerase II Preinitiation Complex Assembly Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Transport of Mature mRNA Derived from an Intronless Transcript tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Educational attainment ( 25201988)
Interacting Genes		57 interacting genes: CSTF2T GLIS2 HMOX1 IL7R INCA1 MCM2 MIR1-2 MIR106B MIR107 MIR122 MIR128-2 MIR138-1 MIR138-2 MIR143 MIR155 MIR15A MIR15B MIR16-2 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200C MIR205 MIR206 MIR20B MIR21 MIR214 MIR221 MIR29A MIR31 MIR34A MIR34B MIR7-1 MIR92A1 MIR92A2 MIR98 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7E MIRLET7F2 MIRLET7G MIRLET7I NEDD4 PAPOLA POLR2A PRRC2A REL TAF11 TAF12 TAF13 TAF5 TAF7	28 interacting genes: APP APPBP2 CPSF1 GTF2B GTF2E1 GTF2F1 H3-4 LZTR1 NFYA NFYB NFYC RELA RXRA RXRB TAF1 TAF10 TAF12 TAF13 TAF2 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBP TRIM24 VDR
Entrez ID		29894	6882
HPRD ID		05823	15980
Ensembl ID		ENSG00000071894	ENSG00000064995
Uniprot IDs		Q10570	Q15544
PDB IDs		6BLY 6BM0 6DNH 6F9N 6FBS 6FUW 6URG 6URO	1BH8 1BH9 6MZD 6MZL
Enriched GO Terms of Interacting Partners?
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