LAMP2 and CTSA

Data Source:
HPRD (in vitro)

		LAMP2	CTSA
Description		lysosomal associated membrane protein 2	cathepsin A
Image
GO Annotations	Cellular Component	Extracellular Space Lysosome Lysosomal Membrane Late Endosome Plasma Membrane Membrane Phagocytic Vesicle Membrane Platelet Dense Granule Membrane Late Endosome Membrane Azurophil Granule Membrane Lysosomal Lumen Autolysosome Membrane Raft Extracellular Exosome Integral Component Of Autophagosome Membrane Membrane Microdomain Ficolin-1-rich Granule Membrane Lysosomal Matrix	Extracellular Region Lysosome Endoplasmic Reticulum Membrane Azurophil Granule Lumen Lysosomal Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome Lumenal Side Of Lysosomal Membrane
	Molecular Function	Protein Binding Enzyme Binding Protein Domain Specific Binding	Carboxypeptidase Activity Serine-type Carboxypeptidase Activity Enzyme Activator Activity
	Biological Process	Platelet Degranulation Protein Targeting Cellular Response To Starvation Protein Import Regulation Of Protein Stability Neutrophil Degranulation Muscle Cell Cellular Homeostasis Protein Stabilization Chaperone-mediated Autophagy Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy Establishment Of Protein Localization To Organelle Autophagosome Maturation Lysosomal Protein Catabolic Process	Proteolysis Glycosphingolipid Metabolic Process Intracellular Protein Transport Regulation Of Protein Stability Neutrophil Degranulation Regulation Of Catalytic Activity Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Chaperone-mediated Autophagy
Pathways		Platelet degranulation Neutrophil degranulation Chaperone Mediated Autophagy	Glycosphingolipid metabolism MHC class II antigen presentation Sialic acid metabolism Defective NEU1 causes sialidosis Neutrophil degranulation
Drugs
Diseases		Danon disease; X-linked vacuolar cardiomyopathy and myopathy	Galactosialidosis
GWAS
Interacting Genes		5 interacting genes: AP4M1 APLNR CTSA PIAS4 UCHL1	45 interacting genes: AHNAK2 AQP2 AQP6 ARL13B ASPH BSND CD79A COQ9 CPLX4 CREB3L1 CSPG5 ERGIC3 FAM209A FKBP7 FNDC9 GLB1 GORAB HIBADH LAMP2 LMNA LTB4R2 MFSD14B MGST3 MUC1 MYG1 NEU1 PSCA REEP4 RHBDD1 RNF122 SAR1A SGMS2 SIGLEC12 SLC18A1 SLC30A2 SPN SSMEM1 STX2 THAP4 TMEM139 TMEM154 TMEM237 TMEM31 TMEM35A TMX2
Entrez ID		3920	5476
HPRD ID		02396	02020
Ensembl ID		ENSG00000005893	ENSG00000064601
Uniprot IDs		P13473	B4E324 P10619 X6R5C5 X6R8A1
PDB IDs		2MOF 2MOM	1IVY 3BP4 3BP7 3BXN 4AZ0 4AZ3 4CI9 4CIA 4CIB 4MWS 4MWT 6WIA
Enriched GO Terms of Interacting Partners?
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