LAMP2 and APLNR

Data Source:
BioGRID (two hybrid)

		LAMP2	APLNR
Description		lysosomal associated membrane protein 2	apelin receptor
Image
GO Annotations	Cellular Component	Extracellular Space Lysosome Lysosomal Membrane Late Endosome Plasma Membrane Membrane Phagocytic Vesicle Membrane Platelet Dense Granule Membrane Late Endosome Membrane Azurophil Granule Membrane Lysosomal Lumen Autolysosome Membrane Raft Extracellular Exosome Integral Component Of Autophagosome Membrane Membrane Microdomain Ficolin-1-rich Granule Membrane Lysosomal Matrix	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding Enzyme Binding Protein Domain Specific Binding	G Protein-coupled Receptor Activity Protein Binding Signaling Receptor Activity Apelin Receptor Activity
	Biological Process	Platelet Degranulation Protein Targeting Cellular Response To Starvation Protein Import Regulation Of Protein Stability Neutrophil Degranulation Muscle Cell Cellular Homeostasis Protein Stabilization Chaperone-mediated Autophagy Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy Establishment Of Protein Localization To Organelle Autophagosome Maturation Lysosomal Protein Catabolic Process	Angiogenesis Blood Vessel Development Vasculogenesis G Protein-coupled Receptor Signaling Pathway Gastrulation Heart Development Adult Heart Development Viral Process Negative Regulation Of CAMP-mediated Signaling Positive Regulation Of Angiogenesis Regulation Of Body Fluid Levels Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Apelin Receptor Signaling Pathway Coronary Vasculature Development Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Positive Regulation Of Inhibitory G Protein-coupled Receptor Phosphorylation
Pathways		Platelet degranulation Neutrophil degranulation Chaperone Mediated Autophagy	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases		Danon disease; X-linked vacuolar cardiomyopathy and myopathy
GWAS
Interacting Genes		5 interacting genes: AP4M1 APLNR CTSA PIAS4 UCHL1	8 interacting genes: AKR1B1 APLN GJB2 LAMP2 MARK4 MTCH1 NDRG4 SETD3
Entrez ID		3920	187
HPRD ID		02396	02503
Ensembl ID		ENSG00000005893	ENSG00000134817
Uniprot IDs		P13473	B2RDH3 B3KQN4 P35414
PDB IDs		2MOF 2MOM	2LOT 2LOU 2LOV 2LOW 5VBL 6KNM
Enriched GO Terms of Interacting Partners?
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