APLNR and LAMP2

Data Source:
BioGRID (two hybrid)

		APLNR	LAMP2
Description		apelin receptor	lysosomal associated membrane protein 2
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Space Lysosome Lysosomal Membrane Late Endosome Plasma Membrane Membrane Phagocytic Vesicle Membrane Platelet Dense Granule Membrane Late Endosome Membrane Azurophil Granule Membrane Lysosomal Lumen Autolysosome Membrane Raft Extracellular Exosome Integral Component Of Autophagosome Membrane Membrane Microdomain Ficolin-1-rich Granule Membrane Lysosomal Matrix
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Signaling Receptor Activity Apelin Receptor Activity	Protein Binding Enzyme Binding Protein Domain Specific Binding
	Biological Process	Angiogenesis Blood Vessel Development Vasculogenesis G Protein-coupled Receptor Signaling Pathway Gastrulation Heart Development Adult Heart Development Viral Process Negative Regulation Of CAMP-mediated Signaling Positive Regulation Of Angiogenesis Regulation Of Body Fluid Levels Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Apelin Receptor Signaling Pathway Coronary Vasculature Development Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Positive Regulation Of Inhibitory G Protein-coupled Receptor Phosphorylation	Platelet Degranulation Protein Targeting Cellular Response To Starvation Protein Import Regulation Of Protein Stability Neutrophil Degranulation Muscle Cell Cellular Homeostasis Protein Stabilization Chaperone-mediated Autophagy Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy Establishment Of Protein Localization To Organelle Autophagosome Maturation Lysosomal Protein Catabolic Process
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Platelet degranulation Neutrophil degranulation Chaperone Mediated Autophagy
Drugs
Diseases			Danon disease; X-linked vacuolar cardiomyopathy and myopathy
GWAS
Interacting Genes		8 interacting genes: AKR1B1 APLN GJB2 LAMP2 MARK4 MTCH1 NDRG4 SETD3	5 interacting genes: AP4M1 APLNR CTSA PIAS4 UCHL1
Entrez ID		187	3920
HPRD ID		02503	02396
Ensembl ID		ENSG00000134817	ENSG00000005893
Uniprot IDs		B2RDH3 B3KQN4 P35414	P13473
PDB IDs		2LOT 2LOU 2LOV 2LOW 5VBL 6KNM	2MOF 2MOM
Enriched GO Terms of Interacting Partners?
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