LALBA and H3C15

Data Source:
BioGRID (pull down)

		LALBA	H3C15
Description		lactalbumin alpha	H3 clustered histone 15
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GO Annotations	Cellular Component	Golgi Membrane Extracellular Space Golgi Lumen	Nucleosome Extracellular Region Nucleus Nucleoplasm Extracellular Exosome
	Molecular Function	Lactose Synthase Activity Calcium Ion Binding	DNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	Lactose Biosynthetic Process Apoptotic Process Signal Transduction Cell-cell Signaling Defense Response To Bacterium	RDNA Heterochromatin Assembly Chromatin Organization Nucleosome Assembly Blood Coagulation Interleukin-7-mediated Signaling Pathway Cellular Protein Metabolic Process Regulation Of Megakaryocyte Differentiation Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Silencing By MiRNA
Pathways		Lactose synthesis	Interleukin-7 signaling Interleukin-7 signaling Pre-NOTCH Transcription and Translation Formation of the beta-catenin:TCF transactivating complex PRC2 methylates histones and DNA Condensation of Prophase Chromosomes Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) HDACs deacetylate histones PKMTs methylate histone lysines HDMs demethylate histones HATs acetylate histones HATs acetylate histones RMTs methylate histone arginines Chromatin modifying enzymes SIRT1 negatively regulates rRNA expression ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression NoRC negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression DNA methylation Transcriptional regulation by small RNAs Activation of anterior HOX genes in hindbrain development during early embryogenesis Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 RNA Polymerase I Promoter Opening RNA Polymerase I Promoter Escape RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function RUNX1 regulates transcription of genes involved in differentiation of HSCs Estrogen-dependent gene expression Meiotic recombination HCMV Early Events HCMV Late Events Transcriptional regulation of granulopoiesis Amyloid fiber formation Factors involved in megakaryocyte development and platelet production
Drugs		Palmitic Acid
Diseases
GWAS		Adiponectin levels ( 24105470) Itch intensity from mosquito bite adjusted by bite size ( 28199695)
Interacting Genes		6 interacting genes: B4GALT1 CRYAA CRYAB H2BC21 H3C15 HSPA8	18 interacting genes: ANP32A CBX5 DNTTIP2 EHMT2 GTF3C4 HDAC9 KDM5A KDM5C LALBA MECP2 NASP PADI4 PRDM1 PRMT6 SETDB1 SUV39H1 UBR7 UHRF1
Entrez ID		3906	333932
HPRD ID		01024
Ensembl ID		ENSG00000167531	ENSG00000203852
Uniprot IDs		A0A080YV01 P00709	Q71DI3
PDB IDs		1A4V 1B9O 1CB3 1HML 3B0I 3B0O 4L41	2IIJ 2X4W 2X4X 2X4Y 3AV1 3DB3 3MO8 3QO2 3R93 4MZF 4MZG 4MZH 4OUC 5B0Y 5B0Z 5B40 5BO0 5CIU 5VAC 6ACE 6FML 6T79 6T7A 6T7B 6T7C 6T7D 6X59 6X5A 6XJD 6Y5D 6Y5E 7BQZ 7BU9 7JO9 7JOA
Enriched GO Terms of Interacting Partners?
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