RND3 and UBXN11

Data Source:
HPRD (two hybrid, in vitro)

		RND3	UBXN11
Description		Rho family GTPase 3	UBX domain protein 11
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoskeleton Plasma Membrane Focal Adhesion Cell Cortex Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle	Cytoplasm Cytoskeleton
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding	Protein Binding Ubiquitin Binding
	Biological Process	Actin Filament Organization Cell Adhesion Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Cell Migration Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs		Guanosine-5'-Triphosphate
Diseases
GWAS		Arterial stiffness (brachial-ankle pulse wave velocity) ( 32790701) Endometriosis ( 23472165) Esophageal adenocarcinoma x gastroesophageal reflux disease interaction ( 29551738) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Neonatal total 25-hydroxyvitamin D levels (fetal genetic effect) ( 32047095) Platelet count ( 31217584) Reticulocyte fraction of red cells ( 32888494) Type 2 diabetes ( 22238593) Urinary metabolite levels in chronic kidney disease ( 29545352)	Monocyte percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Platelet count ( 32888494)
Interacting Genes		8 interacting genes: ARHGAP5 C14orf119 CIT CPLANE2 PLXNB1 ROCK1 SKP2 UBXN11	34 interacting genes: C14orf119 CFAP206 EIF4E EIF4E2 ENKD1 HGS IL16 LENG1 NEK6 PPM1K PRKAA1 PRKAB2 PRPF18 PRPF31 PRR35 PSMA1 RHOBTB3 RND1 RND2 RND3 RNF213 SCNM1 SH2D4A SNRPB TCEANC TLE5 TRAF2 TTC23 USHBP1 VCP VPS9D1 WDR25 ZFYVE9 ZGPAT
Entrez ID		390	91544
HPRD ID		04233	10245
Ensembl ID		ENSG00000115963	ENSG00000158062
Uniprot IDs		B2R838 P61587	Q5T124
PDB IDs		1M7B 2V55 4BG6
Enriched GO Terms of Interacting Partners?
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