RND3

Description		Rho family GTPase 3
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GO Annotations	Cellular Component	Golgi Membrane Cytoskeleton Plasma Membrane Focal Adhesion Cell Cortex Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	Actin Filament Organization Cell Adhesion Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Cell Migration Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization
Pathways
Drugs		Guanosine-5'-Triphosphate
Diseases
GWAS		Arterial stiffness (brachial-ankle pulse wave velocity) ( 32790701) Endometriosis ( 23472165) Esophageal adenocarcinoma x gastroesophageal reflux disease interaction ( 29551738) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Neonatal total 25-hydroxyvitamin D levels (fetal genetic effect) ( 32047095) Platelet count ( 31217584) Reticulocyte fraction of red cells ( 32888494) Type 2 diabetes ( 22238593) Urinary metabolite levels in chronic kidney disease ( 29545352)
Novel Interacting Genes		2 novel interacting genes: CDH5 GCH1
Interacting Genes		8 interacting genes: ARHGAP5 C14orf119 CIT CPLANE2 PLXNB1 ROCK1 SKP2 UBXN11
Entrez ID		390
HPRD ID		04233
Ensembl ID		ENSG00000115963
Uniprot IDs		B2R838 P61587
PDB IDs		1M7B 2V55 4BG6
Enriched GO Terms of Interacting Partners?
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