SERP2 and BSCL2

Data Source:
BioGRID (two hybrid)

		SERP2	BSCL2
Description		stress associated endoplasmic reticulum protein family member 2	BSCL2 lipid droplet biogenesis associated, seipin
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Endoplasmic Reticulum Membrane Lipid Droplet Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	Protein Binding Phospholipid Binding
	Biological Process	Protein Glycosylation Protein Transport Endoplasmic Reticulum Unfolded Protein Response	Lipid Catabolic Process Lipid Storage Lipid Droplet Organization Fat Cell Differentiation Negative Regulation Of Lipid Catabolic Process Positive Regulation Of Cold-induced Thermogenesis Lipid Droplet Formation
Pathways
Drugs
Diseases			Hereditary spastic paraplegia (SPG) Congenital generalized lipodystrophy (CGL) Distal hereditary motor neuropathies (dHMN)
GWAS		Chronic obstructive pulmonary disease ( 30804561) Dupuytren's disease ( 28886342) Fasting insulin (dietary factor interaction) ( 24204828) Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828)	Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		52 interacting genes: ALG10 AQP6 BIK BSCL2 CERS4 CISD2 CKB CYB561 CYBRD1 EBP ELOVL4 ERGIC3 EWSR1 FAM210B FCGR2A FNDC9 FRMD3 GET1 GKN1 GPR152 GPR42 KASH5 LHFPL5 LMNA LYVE1 MFSD14B MTIF3 MUC1 NEMP1 OPRM1 PTGES RETREG3 RNASEK SCN3B SLC10A6 SLC30A4 SLC38A1 SLC38A7 SPACA1 STOM STX1A TIMMDC1 TM4SF18 TM4SF19 TMED8 TMEM106C TMEM14B TMEM179B TMEM237 TMEM31 TMEM80 TMX2	38 interacting genes: ANKRD46 B4GALNT2 BMP10 CLDN19 CMTM7 CPEB2 CXCL9 CYSRT1 ERMP1 FAM20B GABARAPL1 GMCL1 HOXA1 KRTAP6-3 LAT MALL NSG1 OLFM4 PLEKHF2 PLIN1 RPRM SERP1 SERP2 SFTPC SMIM3 SMLR1 STRIT1 TEX37 TMEM19 TMEM218 TMEM222 TRAM1L1 TRARG1 TRIM54 TSPAN2 UPK2 USE1 VAMP3
Entrez ID		387923	26580
HPRD ID		16590	05858
Ensembl ID		ENSG00000151778	ENSG00000168000
Uniprot IDs		Q8N6R1	A0A024R540 A0A024R549 Q96G97
PDB IDs			6DS5
Enriched GO Terms of Interacting Partners?
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