BSCL2 and CPEB2

Data Source:
BioGRID (two hybrid)

		BSCL2	CPEB2
Description		BSCL2 lipid droplet biogenesis associated, seipin	cytoplasmic polyadenylation element binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Lipid Droplet Integral Component Of Endoplasmic Reticulum Membrane	Nucleus Cytoplasm Neuron Projection Synapse Messenger Ribonucleoprotein Complex
	Molecular Function	Protein Binding Phospholipid Binding	Translation Repressor Activity, MRNA Regulatory Element Binding RNA Binding MRNA 3'-UTR Binding GTPase Inhibitor Activity Translation Factor Activity, RNA Binding MRNA 3'-UTR AU-rich Region Binding Ribosome Binding Ribosomal Large Subunit Binding Ribosomal Small Subunit Binding
	Biological Process	Lipid Catabolic Process Lipid Storage Lipid Droplet Organization Fat Cell Differentiation Negative Regulation Of Lipid Catabolic Process Positive Regulation Of Cold-induced Thermogenesis Lipid Droplet Formation	Translation Cellular Response To Insulin Stimulus Negative Regulation Of GTPase Activity Cellular Response To Oxidative Stress Cellular Response To Arsenic-containing Substance Cellular Response To Hypoxia Negative Regulation Of Cytoplasmic Translational Elongation Negative Regulation Of Cytoplasmic Translation
Pathways
Drugs
Diseases		Hereditary spastic paraplegia (SPG) Congenital generalized lipodystrophy (CGL) Distal hereditary motor neuropathies (dHMN)
GWAS		Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Cognitive flexibility ( 30134085) Triglyceride levels ( 32203549)
Interacting Genes		38 interacting genes: ANKRD46 B4GALNT2 BMP10 CLDN19 CMTM7 CPEB2 CXCL9 CYSRT1 ERMP1 FAM20B GABARAPL1 GMCL1 HOXA1 KRTAP6-3 LAT MALL NSG1 OLFM4 PLEKHF2 PLIN1 RPRM SERP1 SERP2 SFTPC SMIM3 SMLR1 STRIT1 TEX37 TMEM19 TMEM218 TMEM222 TRAM1L1 TRARG1 TRIM54 TSPAN2 UPK2 USE1 VAMP3	21 interacting genes: ATG2A ATP1B2 BSCL2 C2CD2L CAPN15 COPS7A ERI3 GAA GABBR1 GPX7 KEAP1 MT-ATP6 NECAB2 OTUB1 PIGS PSAP PUF60 SEMA4B SORBS3 SPARC TUBA1A
Entrez ID		26580	132864
HPRD ID		05858	16744
Ensembl ID		ENSG00000168000	ENSG00000137449
Uniprot IDs		A0A024R540 A0A024R549 Q96G97	A0A5K1VW61 A0A5K1VW71 A0A5K1VW79 A0A5K1VW93 Q7Z5Q1
PDB IDs		6DS5
Enriched GO Terms of Interacting Partners?
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