KRT6A and KRT25

Data Source:
BioGRID (two hybrid)

		KRT6A	KRT25
Description		keratin 6A	keratin 25
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Membrane Keratin Filament Extracellular Exosome	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	Molecular_function Structural Molecule Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Cytolysis By Symbiont Of Host Cells Morphogenesis Of An Epithelium Cytoskeleton Organization Positive Regulation Of Cell Population Proliferation Cell Differentiation Keratinization Wound Healing Defense Response To Gram-positive Bacterium Cytolysis By Host Of Symbiont Cells Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cornification Negative Regulation Of Entry Of Bacterium Into Host Cell	Cytoskeleton Organization Aging Hair Follicle Morphogenesis Keratinization Hair Cycle Intermediate Filament Organization Cornification
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Zinc Zinc acetate
Diseases		Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS		Cutaneous squamous cell carcinoma ( 32041948)	Asthma ( 31959851 30929738) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		38 interacting genes: BEX2 CCDC85B DSP GEM GOLGA2 HGS KDM1A KIFC3 KRT13 KRT15 KRT16 KRT17 KRT18 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT34 KRT35 KRT36 KRT38 KRT40 LMNA MTUS2 NCALD NUP62 SGTA SMARCB1 TCHP TFIP11 TRIM23 TRIM54 TSGA10 TXLNB UBQLN2 WASHC3	22 interacting genes: HGS KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT83 KRT85 KRT86 MORN4 PPL
Entrez ID		3853	147183
HPRD ID		01011	17242
Ensembl ID		ENSG00000205420	ENSG00000204897
Uniprot IDs		A0A0S2Z428 P02538	Q6ZPD6 Q7Z3Z0
PDB IDs		5KI0
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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