KRT13 and KLC3

Data Source:
BioGRID (two hybrid)

		KRT13	KLC3
Description		keratin 13	kinesin light chain 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome	Cytoplasm Kinesin Complex Microtubule Motile Cilium Ciliary Rootlet Neuron Projection
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding Microtubule Binding Kinesin Binding
	Biological Process	Cytoskeleton Organization Keratinization Cornification	Axo-dendritic Transport
Pathways		Keratinization Formation of the cornified envelope	MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases		White sponge nevus
GWAS			Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971)
Interacting Genes		63 interacting genes: ABI2 ABI3 AMOTL2 ANKRD36BP1 APC ATP5PO BLOC1S6 C1orf109 C1orf216 C2CD6 CCHCR1 CCNC CEP57 CEP57L1 DES DNAAF4 EIF4E2 EXOSC5 FANCG FARS2 FBF1 GFAP GLYCTK GOLGA8EP GRAP2 HGS HOOK3 IFT20 KLC3 KLC4 KRT1 KRT2 KRT20 KRT4 KRT6A KRT6B KRT6C KRT7 KRT71 KRT72 KRT74 KRT75 KRT79 KRT8 LSM2 MOS MYH1 MYO15B NEFL PPP1R18 PSMA1 PSMB1 PSMB2 RTL8B SGF29 SPG21 TLE5 TMSB4X TRIM42 TSG101 TXLNA TXLNB ZNF688	42 interacting genes: ABI3 ATP23 BBS5 BICDL2 CBY2 CCNH CENPP CEP57L1 CROCC CT55 DTX2 GEM IHO1 IMP3 KDM1A KIF5A KIF5B KIF5C KLHL21 KRT13 KRT15 MBIP NDC80 NECAB2 NEFL PCBD2 PDE4DIP QARS1 SMARCB1 SNAP47 STX11 TCF4 TSNAX USHBP1 VPS52 WAC WASHC1 YWHAG YWHAH YWHAQ ZNF417 ZNF572
Entrez ID		3860	147700
HPRD ID		01016	03212
Ensembl ID		ENSG00000171401	ENSG00000104892
Uniprot IDs		A1A4E9 P13646	A0A024R0V3 Q6P597
PDB IDs
Enriched GO Terms of Interacting Partners?
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