KLC3 and CROCC

Data Source:
HPRD (two hybrid)

		KLC3	CROCC
Description		kinesin light chain 3	ciliary rootlet coiled-coil, rootletin
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Kinesin Complex Microtubule Motile Cilium Ciliary Rootlet Neuron Projection	Photoreceptor Inner Segment Centrosome Centriole Cytosol Plasma Membrane Actin Cytoskeleton Ciliary Rootlet Extracellular Exosome 9+2 Motile Cilium Subapical Part Of Cell
	Molecular Function	Protein Binding Microtubule Binding Kinesin Binding	Actin Binding Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Kinesin Binding
	Biological Process	Axo-dendritic Transport	Centrosome Cycle Protein Localization Centriole-centriole Cohesion Epithelial Structure Maintenance Ciliary Basal Body Organization Protein Localization To Organelle Photoreceptor Cell Maintenance Positive Regulation Of Cilium Assembly Establishment Of Organelle Localization Positive Regulation Of Protein Localization To Cilium
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971)	Allergic rhinitis ( 22036096) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Hematocrit ( 32888494) Lymphocyte percentage of white cells ( 32888494) Red blood cell count ( 32888494) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		42 interacting genes: ABI3 ATP23 BBS5 BICDL2 CBY2 CCNH CENPP CEP57L1 CROCC CT55 DTX2 GEM IHO1 IMP3 KDM1A KIF5A KIF5B KIF5C KLHL21 KRT13 KRT15 MBIP NDC80 NECAB2 NEFL PCBD2 PDE4DIP QARS1 SMARCB1 SNAP47 STX11 TCF4 TSNAX USHBP1 VPS52 WAC WASHC1 YWHAG YWHAH YWHAQ ZNF417 ZNF572	2 interacting genes: KLC3 RNF152
Entrez ID		147700	9696
HPRD ID		03212	16758
Ensembl ID		ENSG00000104892	ENSG00000058453
Uniprot IDs		A0A024R0V3 Q6P597	Q5TZA2
PDB IDs			6L5H 6L5J
Enriched GO Terms of Interacting Partners?
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