KLC3 and KLHL21

Data Source:
BioGRID (two hybrid)

		KLC3	KLHL21
Description		kinesin light chain 3	kelch like family member 21
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Kinesin Complex Microtubule Motile Cilium Ciliary Rootlet Neuron Projection	Polar Microtubule Cytosol Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Microtubule Binding Kinesin Binding	Ubiquitin-protein Transferase Activity Protein Binding Cullin Family Protein Binding
	Biological Process	Axo-dendritic Transport	Cell Cycle Protein Ubiquitination Regulation Of Cytokinesis Chromosome Passenger Complex Localization To Spindle Midzone Post-translational Protein Modification Cell Division
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971)
Interacting Genes		42 interacting genes: ABI3 ATP23 BBS5 BICDL2 CBY2 CCNH CENPP CEP57L1 CROCC CT55 DTX2 GEM IHO1 IMP3 KDM1A KIF5A KIF5B KIF5C KLHL21 KRT13 KRT15 MBIP NDC80 NECAB2 NEFL PCBD2 PDE4DIP QARS1 SMARCB1 SNAP47 STX11 TCF4 TSNAX USHBP1 VPS52 WAC WASHC1 YWHAG YWHAH YWHAQ ZNF417 ZNF572	4 interacting genes: AURKB IKBKB KLC3 MAPRE1
Entrez ID		147700	9903
HPRD ID		03212	17239
Ensembl ID		ENSG00000104892	ENSG00000162413
Uniprot IDs		A0A024R0V3 Q6P597	Q9UJP4
PDB IDs
Enriched GO Terms of Interacting Partners?
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