KRT2 and KRT25

Data Source:
BioGRID (two hybrid)

		KRT2	KRT25
Description		keratin 2	keratin 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Extracellular Space Nucleus Cytosol Intermediate Filament Membrane Keratin Filament Extracellular Exosome	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein Binding Structural Constituent Of Skin Epidermis	Molecular_function Structural Molecule Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	Keratinocyte Development Epidermis Development Peptide Cross-linking Keratinization Keratinocyte Activation Keratinocyte Proliferation Intermediate Filament Organization Positive Regulation Of Epidermis Development Keratinocyte Migration Cornification	Cytoskeleton Organization Aging Hair Follicle Morphogenesis Keratinization Hair Cycle Intermediate Filament Organization Cornification
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Zinc Copper Anthralin Zinc acetate
Diseases		Ichthyosis bullosa of Siemens
GWAS			Asthma ( 31959851 30929738) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		15 interacting genes: EVPL KRT13 KRT15 KRT16 KRT19 KRT25 KRT27 KRT31 KRT33B KRT35 KRT36 KRT38 KRT40 SIRPA SMAD3	22 interacting genes: HGS KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT83 KRT85 KRT86 MORN4 PPL
Entrez ID		3849	147183
HPRD ID		02560	17242
Ensembl ID		ENSG00000172867	ENSG00000204897
Uniprot IDs		P35908	Q6ZPD6 Q7Z3Z0
PDB IDs
Enriched GO Terms of Interacting Partners?
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