IPO5 and CAB39

Data Source:
BioGRID (two hybrid)

		IPO5	CAB39
Description		importin 5	calcium binding protein 39
Image
GO Annotations	Cellular Component	Nucleus Nuclear Pore Nucleolus Cytoplasm Membrane	Extracellular Region Cytosol Membrane Z Disc Secretory Granule Lumen Extracellular Exosome Serine/threonine Protein Kinase Complex Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Binding GTPase Inhibitor Activity Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity	Protein Binding Kinase Binding Protein Kinase Activator Activity Protein Serine/threonine Kinase Activator Activity
	Biological Process	Protein Import Into Nucleus NLS-bearing Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus Viral Process Negative Regulation Of GTPase Activity Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Response To Amino Acid Stimulus	Cell Cycle Arrest Signal Transduction Positive Regulation Of Peptidyl-threonine Phosphorylation Response To Activity Peptidyl-serine Phosphorylation Activation Of Protein Kinase Activity Intracellular Signal Transduction Neutrophil Degranulation Cellular Hypotonic Response Positive Regulation Of Protein Serine/threonine Kinase Activity Response To Thyroid Hormone Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Potassium Ion Transmembrane Transport
Pathways		vRNP Assembly	Energy dependent regulation of mTOR by LKB1-AMPK Neutrophil degranulation
Drugs
Diseases
GWAS		Peripheral artery disease ( 26488411) Smooth-surface caries ( 24556642)
Interacting Genes		26 interacting genes: ACD BHLHB9 CAB39 CDC42 DPPA3 DTNBP1 H1-0 NUP153 NUP214 NUP62 NUP98 PTEN RAG2 RAN RANBP2 RPL13 RPL23 RPL23A RPL5 RPL7 RPS7 SRP19 SUMO2 TERF1 TINF2 WASL	12 interacting genes: CEP44 GOLGA2 IPO5 MCCD1 MED7 PRKAA1 RSL1D1 SHMT2 STK11 STK24 STRADA STRADB
Entrez ID		3843	51719
HPRD ID		03597	10091
Ensembl ID		ENSG00000065150	ENSG00000135932
Uniprot IDs		B3KWG6 O00410 Q9BVS9	A0A024R496 Q9Y376
PDB IDs		6XTE 6XU2	1UPK 1UPL 2WTK 3GNI 4FZA 4FZD 4FZF 4NZW 4O27
Enriched GO Terms of Interacting Partners?
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