IPO5 and RPL7

Data Source:
BioGRID (affinity chromatography technology, pull down)

		IPO5	RPL7
Description		importin 5	ribosomal protein L7
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GO Annotations	Cellular Component	Nucleus Nuclear Pore Nucleolus Cytoplasm Membrane	Nucleus Nucleolus Cytoplasm Cytosol Focal Adhesion Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Ribonucleoprotein Complex
	Molecular Function	RNA Binding GTPase Inhibitor Activity Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity	DNA Binding RNA Binding MRNA Binding Structural Constituent Of Ribosome Protein Binding Identical Protein Binding
	Biological Process	Protein Import Into Nucleus NLS-bearing Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus Viral Process Negative Regulation Of GTPase Activity Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Response To Amino Acid Stimulus	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Ribosomal Large Subunit Biogenesis
Pathways		vRNP Assembly	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Peripheral artery disease ( 26488411) Smooth-surface caries ( 24556642)	Anthracycline-induced cardiotoxicity in early breast cancer ( 32378780) Crohn's disease ( 22412388)
Interacting Genes		26 interacting genes: ACD BHLHB9 CAB39 CDC42 DPPA3 DTNBP1 H1-0 NUP153 NUP214 NUP62 NUP98 PTEN RAG2 RAN RANBP2 RPL13 RPL23 RPL23A RPL5 RPL7 RPS7 SRP19 SUMO2 TERF1 TINF2 WASL	13 interacting genes: DARS1-AS1 DUX4 IL7R IPO5 NR4A1 PHC2 PPP1CC PTEN RAN SGO1 UBE2I YWHAQ ZNF7
Entrez ID		3843	6129
HPRD ID		03597	05004
Ensembl ID		ENSG00000065150	ENSG00000147604
Uniprot IDs		B3KWG6 O00410 Q9BVS9	P18124
PDB IDs		6XTE 6XU2	4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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