GTF2IRD1 and ATP2C1

Data Source:
BioGRID (two hybrid)

		GTF2IRD1	ATP2C1
Description		GTF2I repeat domain containing 1	ATPase secretory pathway Ca2+ transporting 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding	Calcium Transmembrane Transporter Activity, Phosphorylative Mechanism ATP Binding Proton-exporting ATPase Activity, Phosphorylative Mechanism Manganese Transmembrane Transporter Activity, Phosphorylative Mechanism ATPase Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Multicellular Organism Development Transition Between Slow And Fast Fiber	Calcium Ion Transport Manganese Ion Transport Cellular Calcium Ion Homeostasis Epidermis Development Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Actin Cytoskeleton Reorganization Golgi Calcium Ion Homeostasis Golgi Calcium Ion Transport Ion Transmembrane Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Calcium Ion Transmembrane Transport Manganese Ion Transmembrane Transport Proton Transmembrane Transport
Pathways			Ion transport by P-type ATPases
Drugs			Enflurane Isoflurane Methoxyflurane Desflurane Sevoflurane Calcium
Diseases			Hailey-Hailey disease; Benign familial pemphigus
GWAS		Age at suicide ( 31476763) Aluminium levels ( 26025379) General factor of neuroticism ( 30867560) Neuroticism ( 29255261) Severe influenza A (H1N1) infection ( 26379185) SjÃ¶gren's syndrome ( 24097066) Systemic lupus erythematosus ( 26663301 28714469) Triglyceride levels ( 32203549)	Refractive error ( 32231278) Restless legs syndrome ( 29029846) Waist circumference ( 28552196)
Interacting Genes		24 interacting genes: ALMS1 ATP2C1 CDK20 DCAF6 EXOSC4 GORASP2 HDAC3 HTRA4 KPNA1 KPNA2 KPNA3 KPNA4 MRFAP1L1 PIAS1 PIAS2 PIP4P2 PKP1 PKP2 SELENOS SMAD3 SPTLC1 UBC USP20 ZMYM5	3 interacting genes: F2RL1 GPR35 GTF2IRD1
Entrez ID		9569	27032
HPRD ID		08379	05089
Ensembl ID		ENSG00000006704	ENSG00000017260
Uniprot IDs		E9PFE2 Q9UHL9	B4E295 B4E2Q0 P98194
PDB IDs		2D99 2DN5 2DZQ 2DZR
Enriched GO Terms of Interacting Partners?
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